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Korwa, Daniela Dirgantari
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Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Tinjauan Pustaka Terbaru Peran Omega 3 Pada Dry Eye Anugrahsari, Santi; Lesmana, Andri; Korwa, Daniela Dirgantari; Kumala Sari, Ni Putu Winda
Jurnal MedScientiae Vol. 4 No. 2 (2025): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v4i2.3707

Abstract

Dry eye disease (DED) or dry eye disease is a common condition in every country. Dry eyes can cause symptoms such as discomfort or a cycling sensation, red eyes and a feeling of blockage. Inflammation is one of the underlying pathophysiology of dry eyes. One of the therapeutic approaches that has received major attention is the use of omega-3 fatty acid supplements, which are known to have anti-inflammatory properties and can support eye health. Recent studies have shown that omega-3, especially EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), can improve tear quality, improve meibomian gland function, and increase tear production in people with dry eyes. In addition, omega-3 also plays a role in reducing symptoms of dry eyes, although several studies have shown significant results, but the effectiveness of omega-3 in managing dry eyes still requires further research, especially in determining the optimal dose and duration of therapy. This literature review aims to review the latest developments related to the role of omega-3 in dry eye therapy and explore the underlying effects of omega-3 on dry eyes. Further research is expected to provide stronger evidence regarding the role of omega-3 in dry eye therapy.
Viskositas Darah dan Plasma Pada Talasemia Mayor Korwa, Daniela Dirgantari; Timan , Ina Susianti; Sinsanta, Sinsanta; Sari , Dominica Pita
Jurnal MedScientiae Vol. 4 No. 2 (2025): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v4i2.3961

Abstract

Background: viscosity or viscosity is a physical property that characterizes the resistance to a fluid flow. Fluids have both Newtonian and non-Newtonian properties. Viscosity is divided into blood and plasma viscosity. One of the pathological conditions that can affect blood and plasma viscosity is thalassemia. Thalassemia is a disorder of imperfect globin chain formation resulting in imperfect erythrocyte formation. In 2021, 10,670 cases of thalassemia were reported. The viscosity value in the thalassemia group currently does not have a definite value. Objective: this study involved 57 people who were divided into a control group and a thalassemia group. The control group samples will undergo 5 cc of venous blood collection for a complete hematology and viscosity examination using a digital neo microcapillary device (NMD), but the thalassemia group samples will be taken from the remaining blood for hematology examination before transfusion and viscosity examination. Data analysis was carried out univariately and bivariately using t – test and Mann Whitney test with p < 0.05.Results: it was found that the thalassemia group had a blood viscosity value of 5.67 ± 1.72 cP and plasma viscosity of 3.29 ± 1.2 cP Conclusion: blood viscosity and plasma viscosity in the thalassemia group were higher compared to controls
Co-Authors Andri Lesmana Kumala Sari, Ni Putu Winda Santi Anugrahsari Sari , Dominica Pita Sinsanta Sinsanta Timan , Ina Susianti