Article Per Year (5 Year)
p-Index From 2021 - 2026
0.23
P-Index
This Author published in this journals
All Journal Unesa Journal of Chemistry
Wahyudi, Ainaia Deaqiila
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Energy Materials Science & Nanotechnology

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Sintesis Enkapsulasi Ekstrak Kunyit (Cursuma longa. L) Berbasis Karboksimetil Kitosan sebagai Penghantaran Obat: indonesia Wahyudi, Ainaia Deaqiila; Cahyaningrum, Sari Edi
Unesa Journal of Chemistry Vol. 13 No. 3 (2024): Vol 13 No 3 (2024)
Publisher : Department of Chemistry, Faculty of Mathematics and Natural Sciences, Surabaya State University, located at Jl Ketintang, Surabaya, East Java, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26740/ujc.v13n3.p101-107

Abstract

Curcumin is the main bioactive compound in turmeric (Curcuma longa L.) with high antioxidant activity, yet its application is limited due to poor solubility and low stability under physiological conditions. This study aimed to synthesize and characterize curcumin-encapsulated nanoparticles based on carboxymethyl chitosan (Cur-NPs) as a more stable drug delivery system. The synthesis was performed using the sonication method, while characterization included particle size and polydispersity index (PDI) analysis via PSA dan pH stability testing. The results showed that Cur-NPs had a particle size of 281.3 nm and a PDI of 0.3897, indicating a uniform particle distribution. Cur-NPs exhibited greater stability than turmeric extract across various pH conditions (2-10). These findings demonstrate that curcumin encapsulation using CMC can enhance the stability and release efficiency of curcumin in biological systems.
Co-Authors Sari Edi Cahyaningrum