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Sun Protection Factor Activity of Crude Extract, Nanoparticle Extract, and Lyophilised Powder of Arabian Bidara Leaves (Ziziphus spina-christi (L.) Desf.) Budiati, Anarisa; Kartiningsih; Lady Auria Ananova; Theresia Andrian
Journal of Natural Product for Degenerative Diseases Vol. 3 No. 1 (2025): JNPDD September
Publisher : Faculty of Pharmacy Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58511/jnpdd.v3i1.9023

Abstract

Arabic Bidara Leaves (Ziziphus spina-christi (L.) Desf.) contain flavonoids, including quercetin, which has SPF properties. The goal of this research was to examine the properties and SPF activity of crude extract, nanoparticle extract, and lyophilized powder of Arabian Bidara Leaves. Arabian Bidara Leaves were extracted using the UAE technique with 70% ethanol solvent. The crude extract was converted into nanoparticle extract using the ionic glass process and then freeze dried to produce lyophilized powder.  Then the properties and SPF value were investigated.  The study found that the crude extract of Arabian Bidara Leaves has a brownish green color, 10.42%±0.36 water content, 4.68±0.01 pH, and 19.98±0.15 SPF. The nanoparticle extract has a clear yellow color, distinct odor, liquid form, and can be stored for 5 days without sediment formation. It has a particle size of 268.6 nm±3.75, polydispersity index of 0.547±0.06, zeta potential of -6.07 mV, adsorption efficiency of 89.60%, spherical morphology, and an SPF value of 29.96±0.69. The lyophilized powder is brown, flake-shaped, and has an SPF of 29.27±0.76. The results of this investigation show that the leaves of the Arabian bidara have SPF activity in the ultra protection category.
PIJAT PERINEUM EFEKTIF MENCEGAH RUPTURE PERINEUM PADA IBU BERSALIN : LITERATURE REVIEW Kartiningsih; Siti Farida; Ikrima Rahmasari
Prosiding Seminar Informasi Kesehatan Nasional 2021: SIKesNas 2021
Publisher : Fakultas Ilmu Kesehatan Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (186.774 KB) | DOI: 10.47701/sikenas.v0i0.1266

Abstract

Ruptur perineum merupakan kondisi yang cukup sering terjadi dalam proses persalinan normal. Kondisi ini lebih berisiko terjadi pada ibu primipara, bayi besar, proses persalinan lama, persalinan dengan bantuan alat seperti forceps atau vakum. Perdarahan pasca persalinan akibat rupture perineum menjadi faktor penyebab angka kematian ibu tertinggi kedua di Dunia. Pijatan perineum pada trimester III kehamilan, dapat membantu otot-otot perineum menjadi lebih elastis dan kuat, sehingga menurunkan risiko ruptur perineum pada saat persalinan. Tujuan literature review ini untuk mengetahui efektivitas pijat perineum dalam mencegah ruptur perineum pada ibu bersalin. Metode yang digunakan yaitu dengan metode penelusuran artikel jurnal di database sciences dari Google Scholar dengan menggunakan kata kunci sesuai topik yang relevan dan didapatkan sebanyak 6 jurnal yang sesuai dengan kriteria inklusi dari 10 penelusuran artikel jurnal yang diperoleh. Berdasarkan hasil penelitian, pijat perineum pada ibu hamil efektif mencegah kejadian ruptur perineum pada saat persalinan. Pijat perineum yang dilakukan secara rutin sejak usia kehamilan > 34 minggu efektif memperkecil risiko ruptur perineum, terutama pada ibu primipara karena otot-otot perineum dan vagina menjadi lebih elastis dan kuat. Diperlukan keteraturan pijat perineum agar diperoleh manfaat yang optimal. Peran bidan, dukungan suami serta keluarga sangat diperlukan bagi ibu hamil dalam keteraturan melakukan pijat perineum.Kata Kunci : pijat perineum, rupture perineum
Formulation of Instant Granule of Japanese Taro Tuber Extract (Colocasia esculenta L. Schoot) Based on Milk With Various Binders for Stunting Prevention Budiati, Anarisa; Kartiningsih; Satrio Damar Wicaksono
Journal of Natural Product for Degenerative Diseases Vol. 1 No. 2 (2024): JNPDD March
Publisher : Faculty of Pharmacy Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58511/jnpdd.v1i2.6106

Abstract

Japanese taro root extract (Colocasia esculenta L. Schoot) includes Fe and Zn, which the body need to prevent stunting. The goal of this investigation was to see how different binder types affected the physical and chemical properties of instant granule preparations. The formula for an instant granule dry extract of Japanese taro root was developed using the wet granulation method with various binders, including PVP (F1), Mucillago amili (FII), and Na-CMC (FIII), and then tested for physical, chemical, and Fe and Zn content using Atomic Absorption Spectrophotometry. The test findings showed that the flow rate of instant granules of Japanese taro root extract formulations I, II, and III was (4.6840-4.7956) g/s, with an angle of repose of 26.86-31.08°. The granules had particle sizes ranging from 670,2295-703,2438 μm, a compressibility index of 15.91-19.00%, and moisture content of 2.80-3.58%. The immediate granule test was performed after being dispersed in water; formulations I, II, and III had dispersion periods of 40.33-50.33 seconds, specific gravity of 1.0099-1.0101 g/mL, viscosity of 1.3589-1.6352 cps, sedimentation volume of 0.940-0.955, and pH of 6.60-6.65. Formulas II using 10% muchilago amyl binder had the greatest Fe and Zn levels, at 34.40 mg/kg and 16.19 mg/kg, respectively. The statistical test revealed a significant effect of different binders on angle of repose, moisture content, dispersion time, pH, and viscosity of Japanese taro root extract granules (p-value < 0.05).