<![CDATA[Introduction Fever is one of the most common side effects of DPT immunization in infants, often causing concern among parents. Data from Puskesmas Remboken in 2023 showed that 32.6% of infants experienced Post-Immunization Adverse Events (KIPI), with fever being the most frequent at 29.5%, followed by injection site pain (8.3%), swelling (0.97%), and other reactions (0.57%). Onion compresses are a safe, natural alternative for reducing fever because the compounds they contain help lower body temperature through heat transfer. This study aims to analyze the effectiveness of a combination of red onion and Virgin Coconut Oil (VCO) compresses in reducing fever in infants after DPT immunization at Puskesmas Remboken, Minahasa Regency. Method the research uses a quasi-experimental design with a one-group pretest-posttest approach. The study involved 33 infants selected using accidental sampling based on inclusion and exclusion criteria. Data analysis was conducted using the paired samples t-test and the experiment was conducted for ± 30 days. Result showed that the t-test yielded a p-value of 0.000 (< 0.05), indicating that the combination of red onion and VCO compresses was effective in reducing infant body temperature. Conclusion this combination therapy is an effective, safe, and easily applicable non-pharmacological method for managing fever in infants after DPT immunization. It also has the potential to reduce dependence on antipyretics and improve the quality of infant care.]]>
