Article Per Year (5 Year)
p-Index From 2020 - 2025
0.23
P-Index
This Author published in this journals
All Journal BiosciED: Journal of Biological Science and Education
Maharani Putri, Zahra
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Immunology & microbiology Other

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Efektivitas Ekstrak Buah Pir Dalam Menghambat Streptococcus Pyogenes Pada Media NA : Effectiveness of Pear Fruit Extract in Inhibiting Streptococcus Pyogenes in NA Media Aditami, Tanzilal; Jannah, Ena S A R; Maharani Putri, Zahra
BiosciED: Journal of Biological Science and Education Vol. 6 No. 1 (2025): BiosciED June 2025
Publisher : FKIP, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/bed.v6i1.22192

Abstract

This study aims to determine the effectiveness of pear fruit extract (Pyrus pyrifolia) in inhibiting the growth of Streptococcus pyogenes in vitro using the disk diffusion method on Nutrient Agar (NA) media. Infection by Streptococcus pyogenes is the main cause of acute pharyngitis and often shows resistance to certain antibiotics, so natural treatment alternatives are needed. Pear fruit extract was tested at concentrations of 25%, 50%, 75%, and 100%. The test was conducted using the disk diffusion method on Nutrient Agar (NA) media, with inhibition zone measurements taken after incubation for 48 hours at 37°C. The results showed that all concentrations of the extract were able to form inhibition zones, with the 100% concentration producing the largest inhibition zone. Analysis showed a correlation between increasing extract concentration and antibacterial effectiveness, although it was not completely linear. The content of phytochemical compounds such as flavonoids and phenols in pears is thought to play a role in disrupting bacterial cell membranes and cell metabolism. This study supports the potential of pears as a natural antibacterial agent against Streptococcus pyogenes and contributes to the development of natural-based therapies to overcome antibiotic resistance.
Co-Authors Aditami, Tanzilal Jannah, Ena S A R