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All Journal Jurnal Biosense Bioscientist : Jurnal Ilmiah Biologi
Arvanda, Diela Gista
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences

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Analisis Studi Kasus Mengenai Usia Ibu dan Gambaran Fisik Penderita Sindrom Down Arvanda, Diela Gista; Izzah, Annisa Nurul
JURNAL BIOSENSE Vol 6 No 02 (2023): Edisi Desember 2023
Publisher : Program Studi Biologi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas PGRI Banyuwangi, Jalan Ikan Tongkol No 01, Telp (0333) 421593, 428592 Banyuwangi 68416

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36526/biosense.v6i02.3312

Abstract

Down syndrome or trisomy 21 is the most common genetic disorder among other genetic disorders. The definition of Down syndrome is a chromosomal abnormality in which there is an extra copy of chromosome 21 due to non-disjunction, mosaicism or the rarest occurrence is translocation. The age of the mother when pregnant is one of the factors causing Down syndrome, the older the mother's age, the greater the chance of Down syndrome. The development of Down syndrome children is different from other normal children, so special care and parenting are needed. The purpose of this research is to analyze through case studies of Down syndrome patients aspects of birth occurrence, aspects of child growth and development, and aspects of the physical description of Down syndrome patients. The results of this study indicate that many factors can influence the occurrence of Down syndrome, namely genetic factors, radiation factors, and the age of the mother. If Down syndrome children receive a form of therapy, health care, and supportive parenting and environment. Then Down syndrome children can adapt well such as how to communicate and interact.
Pengaruh Pemberian Ekstrak Kulit Buah Rambutan (Nephelium lappaceum L.) terhadap Penurunan Kadar Trigliserida pada Tikus Putih (Sprague dawley) Model Obesitas Arvanda, Diela Gista; Lisdiana
Bioscientist : Jurnal Ilmiah Biologi Vol. 13 No. 4 (2025): December
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v13i4.18403

Abstract

This study aims to determine the effect of rambutan peel extract on triglyceride levels in Sprague Dawley obese rats. This study uses experimental laboratory research with a randomized posttest control group design. The population used in this study consisted of healthy male Sprague Dawley white rats aged 6–8 weeks, with an initial body weight of 160–200 grams and no physical abnormalities. Twenty-five Sprague Dawley rats were divided into five treatment groups, namely the control group (K-), the obesity group (K+), the Ellagic acid-induced group (T1), the RPE 15 mg/kgBW dose group (T2), and the RPE 30 mg/kgBW dose group for 30 days. Triglyceride levels were analyzed using one-way ANOVA and Tukey HSD post hoc test. The results showed that rambutan peel extract had a significant effect on triglyceride levels. The 15 mg/kgBW dose group showed a more effective reduction compared to other doses. It can be concluded that rambutan peel extract has the potential to reduce triglyceride levels in obese rats.
Co-Authors Izzah, Annisa Nurul Lisdiana