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Prediksi Resiko Kematian Penderita Gagal Ginjal KronisDengan Voting Classifier Dan Random Forest Pada Data Tidak Seimbang Amaliana, Luthfatul; Ani Budi Astuti; Rossanda Sevia Gadis; Naurah Atikah Rabbani; Nabila Ayunda Sovia
Jurnal Teknologi Informasi dan Ilmu Komputer Vol 12 No 4: Agustus 2025
Publisher : Fakultas Ilmu Komputer, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25126/jtiik.124

Abstract

Gagal ginjal kronis merupakan salah satu penyakit serius yang dapat menyebabkan kematian jika tidak terdeteksi dan ditangani secara dini. Penelitian ini bertujuan memprediksi risiko kematian pada pasien gagal ginjal kronis menggunakan metode ensemble learning, yaitu random forest dan voting classifier (hard voting dan soft voting). Voting classifier digunakan untuk menggabungkan prediksi dari beberapa model klasifikasi tunggal, di mana hard voting mengambil keputusan berdasarkan suara terbanyak, sedangkan soft voting mempertimbangkan rata-rata probabilitas prediksi. Data yang digunakan pada penelitian ini merupakan data sekunder dari RSUD Dr. Saiful Anwar, Kota Malang. Proporsi pasien rawat inap yang pulang dalam kondisi meninggal lebih kecil dibanding kondisi tidak meninggal. Kondisi data tidak seimbang ini menyebabkan model cenderung bias terhadap kelas mayoritas. Untuk mengatasi hal tersebut, synthetic minority over-sampling technique (SMOTE) diterapkan guna menyeimbangkan distribusi kelas. Selain itu, random forest dipilih karena kemampuannya dalam menangani ketidakimbangan data melalui pembobotan pada pohon-pohon keputusan, sehingga mengurangi bias terhadap kelas mayoritas. Evaluasi performa model dilakukan menggunakan metrik akurasi, presisi, dan recall. Hasil evaluasi menunjukkan bahwa random forest memberikan kinerja terbaik dengan akurasi 77%, presisi 36%, dan recall 60%, mengungguli hard voting dan soft voting. Penggunaan random forest dan SMOTE terbukti meningkatkan prediksi pada kelas minoritas, yang sangat penting dalam mendeteksi pasien berisiko kematian tinggi. Pendekatan ini dapat membantu dalam deteksi dini dan pengelolaan yang lebih baik terhadap pasien gagal ginjal kronis, sehingga berpotensi menurunkan angka kematian akibat penyakit ini.   Abstract Chronic kidney disease (CKD) is a life-threatening condition that can lead to fatal outcomes if not diagnosed and treated promptly. This study aims to forecast mortality risk in CKD patients using ensemble learning techniques, including random forest an d voting classifier (hard voting and soft voting). The voting classifier combines predictions from various single classification models, with hard voting selecting outcomes based on majority decisions, while soft voting averages prediction probabilities. The data used in this study is secondary data from RSUD Dr. Saiful Anwar, Malang City. The proportion of hospitalized patients who were discharged in a deceased condition is smaller than those who were discharged alive. This imbalance in the data causes the model to be biased toward the majority class. However, models tend to favor the majority class when dealing with imbalanced data. To mitigate this, the synthetic minority over-sampling technique (SMOTE) was applied to balance the class distribution. Random forest was also selected for its ability to manage data imbalance through weighted decision trees, reducing bias toward the majority class. Model performance was evaluated using metrics such as accuracy, precision, and recall. Results indicated that random forest outperformed hard voting and soft voting, achieving 77% accuracy, 36% precision, and 60% recall. The combination of random forest and SMOTE significantly enhanced the prediction of minority class outcomes, which is essential for identifying high-risk patients. This method has the potential to support early detection and improved management of CKD patients, thus reducing mortality rates associated with the disease.
Differences in Serum Soluble Cluster of Differentiation 163 levels and Monocyte Lymphocyte Ratio between Drug-Resistant and Drug-Sensitive Lung Tuberculosis Nuansa Paramita; Ngakan Putu Parsama Putra; Susanthy Djajalaksana; Rezki Tantular; Ani Budi Astuti
Jurnal Respirologi Indonesia Vol 46 No 4 (2026)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/

Abstract

Background: Tuberculosis (TB) remains a major health problem, particularly in Indonesia. Early diagnosis of drug-sensitive (DS-TB) and drug-resistant tuberculosis (DR-TB) remains challenging due to limited access to molecular diagnostics in peripheral healthcare settings and difficulties in sputum specimen collection. This study evaluated serum soluble CD163 (sCD163) and monocyte-to-lymphocyte ratio (MLR) for diagnostic utility. Methods: A cross-sectional study included 32 DS-TB patients, 30 DR-TB patients, and 26 healthy controls. Serum sCD163 was measured using ELISA, while MLR was calculated from complete blood counts. Statistical analyses included Kruskal–Wallis, Dunn's post hoc, Spearman correlation, and Cross Tabulation analysis for each comparisons. Results: Both DR-TB and DS-TB showed significantly higher sCD163 levels than controls (p=0.003), with no difference between TB groups (p=0.676). Similarly, MLR was higher in both TB groups than controls (p<0.001), without intergroup differences (p=0.217). Serum sCD163 positively correlated with MLR (r=0.319; p=0.003). Patients with sCD163 >85.97 ng/mL and MLR >0.59 had 1.01-fold and 1.29-fold higher odds of DR-TB, respectively, although these associations were not statistically significant. sCD163 in DR-TB showed slightly lower sCD163 and MLR than DS-TB. This may reflect a more preserved innate immune response with active monocyte–macrophage activation in DS-TB, whereas chronic antigen exposure in DR-TB may induce immune dysregulation and immune exhaustion, reducing monocyte activity and biomarker release. Conclusion: sCD163 and MLR may serve as supportive biomarkers for active TB diagnosis especially DR-TB, with MLR showing greater diagnostic value.