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asrini, diana nur
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Health Professions Medicine & Pharmacology Public Health

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Reexpansion Pulmonary Edema asrini, diana nur
Majalah Kedokteran Andalas Vol. 46 No. 3 (2023): Supplementary July 2023
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v46.i5.p858-869.2023

Abstract

AbstrakReexpansion pulmonary edema (REPE) adalah edema paru non kardiogenik, biasanya bersifat unilateral. yang terjadi pada paru yang mengembang setelah periode kolaps akibat pneumotoraks atau efusi pleura. Walaupun kejadiannya jarang terjadi, namun tingkat mortalitasnya cukup tinggi. Faktor risiko REPE adalah multifaktorial dan etiologinya belum sepenuhnya jelas. Pendekatan klinis terbaik untuk REPE adalah dengan pencegahan. Penatalaksanaan REPE biasanya bersifat konservatif dan suportif yaitu dengan pemberian oksigen tambahan, dukungan ventilasi dan pemantauan hemodinamik.  Kata kunci: edema paru reekspansi, efusi pleura, pneumotoraks, pemberian oksigen tambahan, ventilasiAbstractReexpansion pulmonary edema (REPE) is non cardiogenic pulmonary edema, usually unilateral that occurs in the lung that expands after a period of collapse due to pneumothorax or pleural effusion. Although it is a rare case, the mortality rate is quite high. The risk factors for REPE are multifactorial and the etiology is not completely clear. The best clinical approach to REPE is prevention. Management of REPE is usually conservative and supportive with supplemental oxygen, ventilatory support, and hemodynamic monitoring Keywords: reexpansion pulmonary edema, pleural effusion, pneumothorax, supplemental oxygen, ventilatory support
Association Between Ferritin Levels and Sepsis in Patients with COVID-19 at Dr. M. Djamil Hospital Asrini, Diana Nur; Khairsyaf, Oea; Afriani, Afriani
Jurnal Respirologi Indonesia Vol 44 No 1 (2024)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v44i1.545

Abstract

Background: Ferritin is an important mediator of immunomodulatory dysregulation and pro-inflammatory effects, which contribute to cytokine storms that could lead to sepsis in a critically ill patients with COVID-19. The role of ferritin as a biomarker of sepsis in those patients is yet fully understood. The aim of this study is to investigate an association between ferritin levels and sepsis in patients with COVID-19.Method: This study was a retrospective, cross-sectional study of 474 COVID-19 hospitalized patients at Dr. M. Djamil Hospital, Padang.Result: Most of the COVID-19 patients in this study were between the ages of 18 and 49 (38,61%), female (55.91%), with moderate clinical illness (40.50%), and had one comorbidity (41,14%) with obesity as the most common comorbidity (37.97%). More than half of patients (54,22%) had ferritin levels of ≥500 ng/mL (median 1,201 ng/mL with a range of 503–12,010 ng/mL). The incidence of sepsis was significantly higher in the group whose ferritin level was ≥ 500 ng/ml compared to those with less ferritin level (P<0.001; OR=3.33; 5.99% vs 17.91%; CI 95%=1.74-6.36).Conclusion: There is a statistically significant association between the ferritin level and sepsis in patiens with COVID-19 at DR M Djamil Hospital.
Co-Authors Afriani Afriani Oea Khairsyaf