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Applications of bioactive compounds of traditional Chinese medicine in breast cancer management Srivastava, Saumya; Upadhye, Vijay Jagdish; Prasad, Madhulika Esther; Singh, Pallavi
Journal of Applied Pharmaceutical Research Vol. 13 No. 4 (2025)
Publisher : Creative Pharma Assent

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69857/joapr.v13i4.935

Abstract

Background: Over the past few decades, the prevalence of breast cancer has been rapidly increasing, making it one of the most prevalent malignancies diagnosed in women globally. Traditional Chinese Medicine (TCM) has gained attention as a potential approach for managing breast cancer by boosting immune response, inhibiting cancer-related gene activity, and alleviating the adverse effects of radiotherapy and chemotherapy. TCM offers a valuable framework for therapeutic systems and scientific exploration that is widely practiced in many regions worldwide, primarily in China, Korea, and Japan. The herbal components of TCM exhibit complex biological activities that influence multiple aspects of cancer progression, including cell proliferation, programmed cell death (apoptosis), immune modulation, and tumor-host interactions. Methodology: A systematic literature review was conducted using peer-reviewed articles published between 2017 and 2024. Relevant data were collected from publicly available scientific databases. Non-English, Conference papers, and duplicate studies were excluded to ensure the inclusion of high-quality and relevant research findings. Result and Discussion: Analysis revealed that specific bioactive compounds in TCM exhibit significant anti-cancer effects. For example, ginsenoside Rg3 inhibited tumor growth by 45% in vivo, while curcumin reduced MDA-MB-231 breast cancer cell viability by 60% at 20 μM. Conclusion: The promise of TCM, especially its bioactive components and medicinal herbs in the treatment of breast cancer, is the main highlight of this paper. Additionally, it highlights the key scientific databases that provide critical insights into TCM research while exploring the therapeutic mechanisms of Chinese herbs and their bioactive components in mitigating breast cancer progression.        
Unveiling the Nexus of Digital Transformation and Change Management: A Pioneering Bibliometric Analysis Singh, Pallavi; joshi, Rinki; Pathak, Prachi; Aswal, Vaishali
Journal of Accounting, Business and Management (JABM) Vol 33 No 1 (2026): April
Publisher : STIE Malangkucecwara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31966/jabminternational.v33i1.1588

Abstract

As the digital market grows, businesses must embrace digital transformation (DT) to remain competitive. The integration of digital technologies has redefined business operations, models, and customer engagement. However, successful DT is not solely a technological initiative—it requires robust change management (CM) to address resistance, enhance organisational agility, and ensure long-term sustainability. This study presents the first bibliometric analysis to explore the intersection of DT and CM, offering a comprehensive view of how scholarship in these domains has evolved. Using VOSviewer and Biblioshiny, we conduct co-citation and co-occurrence mapping to identify influential studies, emerging trends, and persistent research gaps. Scopus was chosen as the primary database for material processing, given its extensive coverage of peer-reviewed literature across disciplines. In addition, data sources such as surveys, databases, and digital archives were integrated to provide valuable insights and contextual depth, ensuring a more nuanced and holistic analysis. The findings highlight the growing importance of DT and underscore the critical role of leadership, skill development, and effective technology implementation in driving change. Our study reveals that research in this area increasingly emphasizes the integration of technology with management practices and employee engagement. By combining bibliometric analysis with diverse data sources, this article not only maps the trajectory of DT and CM research but also identifies opportunities for future investigation. Ultimately, the study calls for a comprehensive approach that blends technological innovation, managerial processes, and workforce adaptability to help organisations thrive in an era of rapid digital change.