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Novia Yolanda
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Health Professions Public Health

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Colchicine – from Gout to Covid-19 Ekadana Prayoga Suryadi; Keith Justine Thiotansen; Reynaldi Hardianto Saputra; Priscilla Angeline; Novia Yolanda
Journal for Quality in Public Health Vol. 5 No. 2 (2022): May
Publisher : Master of Public Health Program Institut Ilmu Kesehatan STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/jqph.v5i2.385

Abstract

Colchicine is a toxic and carcinogenic alkaloid obtained from the plant extract Colchium autumnale and has been used to treat arthritis (gout) for centuries. The results of clinical trials show that low-dose colchicine is effective for the management of acute gout as well as for long-term maintenance profiling (53) and the use of colchicine is known to reduce the symptoms of inflammatory responses related to COVID-19 and reduce the frequency of other manifestations such as pulmonary infiltrates, headaches and arthralgia. However, so far studies have shown that colchicine is not used as an initial or primary treatment to treat COVID-19 but as a treatment that is "off-label" in response to hyper-inflammation caused by the release of cytokines (52).
Co-Authors Ekadana Prayoga Suryadi Keith Justine Thiotansen Priscilla Angeline Reynaldi Hardianto Saputra