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All Journal Journal of Medical Genetics and Clinical Biology (JMGCB)
Mutlag, Salam Khalid
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Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing

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Estimated Glycation End Products and Oxidative Status in Renal Failure Patients Mutlag, Salam Khalid; Mukhlif1, Mohanad Hammo
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 2 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT. Antis International Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i2.369

Abstract

The present study conducted to assess the Glycation end products and oxidative status of in patients with renal failure. 100 patients that have had CKD for less than 2 years have been diagnosed by a doctor. A control group of 40 stable individuals was selected. From October 2021 to February 2022, patients were confirmed to be sick with chronic renal disease at Azadi Teaching Hospital and Al-Jumhuri Hospital. ‎the results showed that the largest age group of patients was > 60 years with percent (39%). Body Mass Index (BMI) of patients was 18.5-24.9 kg with percent (52%). Residential Area of patients was urban with percent (83%). Smoking Status of patients was non-smoking with percent (68%). The current outcomes demonstrated a reduction in the concentration of total protein that is significant (P<0.05), albumin and globulin in patients compare with healthy volunteers. On the other hand, the results show a significant (P<0.05) elevated in levels of carbonyl and amino group, while decreased in thiol levels in patients compare with healthy volunteers. Otherwise, the Glycation level shows significant (P<0.05) elevated in in patients compare with healthy volunteers. Its concluded that the CKD lead to elevated Glycation level and changes in oxidative status.
Co-Authors Mukhlif1, Mohanad Hammo