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All Journal The Indonesian Journal of General Medicine
Josephine
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Dentistry Health Professions Medicine & Pharmacology Public Health Veterinary

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A Systematic Review of Epidemiological characteristics, routine laboratory diagnosis, clinical signs and risk factors for hand, foot and mouth disease Angela; Josephine
The Indonesian Journal of General Medicine Vol. 1 No. 6 (2024): The Indonesian Journal of General Medicine
Publisher : International Medical Journal Corp. Ltd

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Abstract

Background: Hand, foot and mouth disease (HFMD) is a common, mild viral infection that mostly affects children under 5 years of age. The causative agent is typically enterovirus A (EV-A), which includes the serotypes Coxsackievirus A and enterovirus A71, A76, and A89–92; serotypes of enterovirus B are sometimes detected. Methods: This systematic review focused on full-text English literature published between 2014 and 2024 using the PRISMA 2020 guidelines. Editorials and review pieces published in the same journal as the submission without a DOI were not accepted. Result: Five publications were found to be directly related to our ongoing systematic examination after a rigorous three-level screening approach. Subsequently, a comprehensive analysis of the complete text was conducted, and additional scrutiny was given to these articles. Conclusion: The detection of clinical risk factors and the temporal, spatial and socio-demographic distribution epidemiological characteristics of severe HFMD contribute to the timely diagnosis and intervention, the results of this study can be the reference of further clinical and public health practice.
Co-Authors Angela