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All Journal Journal Of World Science Indonesian Health Journal
Atique, Rameen
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Computer Science & IT Dentistry Economics, Econometrics & Finance Engineering Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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Brief Overview of MERS: Middle East Respiratory Syndrome Nadeem, Ayesha; Saeed, Hafiza Arshi; Talib, Ambreen; Shah, Rabbya Rayan; Atique, Rameen; Samad, Abdul
Journal of World Science Vol. 3 No. 11 (2024): Journal of World Science
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jws.v3i11.1226

Abstract

Middle East Respiratory Syndrome (MERS) is a zoonotic disease caused by MERS-CoV, a beta coronavirus with a mortality rate of approximately 35%. The disease exhibits a wide range of clinical symptoms, from mild respiratory issues to severe conditions like multi-organ failure and pneumonia. Person-to-person transmission has led to significant hospital and community outbreaks, underscoring the urgent need for effective infection control measures. This study explores MERS-CoV's epidemiology, pathogenesis, and transmission dynamics, aiming to enhance understanding of its replication, spread, and control strategies due to limited pharmaceutical interventions. A comprehensive review of current literature was conducted, focusing on epidemiological data, genetic characteristics, and transmission patterns across affected regions, including the Middle East, Asia, Africa, and North America. Findings indicate that MERS-CoV originated from recombination events in the spike protein of African dromedaries and spread to the Arabian Peninsula via camels. The virus affects not only humans but also domestic animals like sheep, cattle, horses, and pigs, with global transmission facilitated by travelers, resulting in outbreaks in Asia and North America. Despite extensive research, no effective vaccines, antiviral drugs, or immune therapies control MERS-CoV. The findings emphasize the high pandemic potential of MERS-CoV due to its mortality rate and lack of effective treatments, highlighting the need for strict infection control and further research into viable therapeutic options.
Brief Overview on Rabies: A Fatal and Preventable Virus Samad, Abdul; Naveed, Areesha; Nurul Alam, AMM; Atique, Rameen; Muazzam, Ayesha; Anwar, Bushra; Arshi Saeed, Hafiza; Zahra, Maryam; Rana, Tehreem; Hossain, Md. Jakir
Indonesian Health Journal Vol. 3 No. 1 (2024): Indonesian Health Journal
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/ihj.v3i1.383

Abstract

Rabies is a fatal and acute infection of the brain. The virulence factor of this infection is the Rabies virus, which belongs to the Rhabdoviridae family. It is a zoonotic disease that can be transmitted from animals to humans.  The common ways of transferral of Rabies in humans are the transmission of rabies by the bite of a rabid animal and transmission due to saliva and consumption of meat and milk of rabid animals. Some wild animals, e.g., skunks, dogs, raccoons, foxes, and bats, can also transfer rabies in humans, mammals, and other animals. The incubation period of Rabies is at least 2 weeks to a maximum of 6 years, with an average duration of 2 to 3 months. Given its status as a significant zoonotic disease, it is crucial to have an accurate and prompt diagnosis to facilitate early treatment and implement effective measures for prevention and control. This study comprehensively analyzes epidemiology, transmission, etiology, advancements in diagnostics, immunization, therapy methods, and effective prevention and control techniques. The main objective of this study is to brief the threat of rabies and its management along with providing some brief knowledge related to rabies. The web sources (e.g., Google Scholar, Pubmed) were used to collect data regarding Rabies and briefly explained. As a result, it is clear that rabies is a big threat to the whole world so management strategies are required to target and overcome this threat. This study concludes that the Rabies virus can be managed by following the preventive and managemental strategies.
Co-Authors Abdul Samad Anwar, Bushra Arshi Saeed, Hafiza Hossain, Md. Jakir Muazzam, Ayesha Nadeem, Ayesha Naveed, Areesha Nurul Alam, AMM Rana, Tehreem Saeed, Hafiza Arshi Shah, Rabbya Rayan Talib, Ambreen Zahra, Maryam