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All Journal INDONESIAN JOURNAL OF MEDICAL LABORATORY SCIENCE AND TECHNOLOGY Jurnal Kesehatan Tambusai
Emma, Ismawatie
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Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Social Sciences

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INCOMPATIBLE DARAH DONOR TERHADAP PASIEN GAGAL GINJAL KRONIK YANG MENJALANI HEMODIALISA DI RUMAH SAKIT BAYUKARTA KARAWANG Emma, Ismawatie; Dewi, Yulia Ratna; Gunawan, Lucia Sincu; Wahyuningsih, Sandra Tri
Jurnal Kesehatan Tambusai Vol. 5 No. 1 (2024): MARET 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v5i1.25705

Abstract

Penyakit gagal ginjal kronik (GGK) merupakan penurunan dari fungsi ginjal secara kronis yang memerlukan waktu lama. Hemodialisis (cuci darah) merupakan salah satu langkah untuk terapi pengganti ginjal yang dapat digunakan pada pasien penderita dengan penurunan fungsi ginjal baik yang akut maupun kronik. Pasien gagal ginjal kronik yang menjalani terapi tindakan hemodialisa (HD) reguler ditransfusi dengan jenis darah transfusi PRC (Packed Red Cell). Namun saat pemeriksaan uji cocok serasi darah sering sekali terjadinya masalah crossmatching incompatible. Tujuan penelitian ini adalah untuk mengetahui adanya incompatible darah donor terhadap pasien penderita gagal ginjal kronik yang menjalani terapi hemodialisa di Rumah Sakit Bayukarta Karawang. Metode penelitian dilakukan secara deskriptif. Bahan yang digunakan yaitu data sekunder hasil crossmatching pada pasien penderita Gagal Ginjal Kronik (GGK) yang menjalani Hemodialisa (HD) di Rumah Sakit Bayukarta Karawang. Analisis data secara deskriptif yaitu inkompatibilitas ditabulasi dengan berdasarkan hasil crossmatch yaitu persentase darah inkompatibel pada pasien penderita gagal ginjal kronik yang menjalani terapi hemodialisa (HD). Hasil penelitian dapat disimpulkan bahwa dari hasil uji crossmatching sebanyak 75 pasien penderita gagal ginjal kronik (GGK) yang menjalani hemodialisis regular dan transfusi darah di rumah sakit terdapat inkompatibel 24 (31%) dengan persentase inkompatibilitas kategori IV sebanyak 20 (27%) dan inkompatibilitas kategori V sebanyak 4 (4%).
Spermatozoa Morphology Examination Using Lenshooke SQA X1 Pro Compared with Manual Method Purwanto, Adhipireno; Purwanto, Edy; Sulijaya, Suyono Seso; Emma, Ismawatie; Budi, Santoso; Setiawan, Limijadi Edward Kurnia
JURNAL INDONESIA DARI ILMU LABORATORIUM MEDIS DAN TEKNOLOGI Vol 4 No 1 (2022): The future of diagnostic laboratory testing
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/ijmlst.v4i1.2059

Abstract

According to World Health Organization data, 30-40% of infertility is caused by male factors. The morphology of normal spermatozoa is an indicator of male fertility, and it is known by manual or automatic sperm analysis. Lenshooke SQA X1 PRO automatic equipment comes along with the development of laboratory equipment automation technology. The working principle of this tool is by shining light on the object of examination, then the camera with high resolution, with the facility of an optical lens will take a picture of the object. The database recorded by the camera is analyzed by the algorithm. The research objective was to test the suitability of the Lenshooke SQA X1 PRO automatic tool with manual method as the Gold Standard. Subjects in this study were patients who carried out semen analysis tests at the Clinical Pathology Laboratory of RSIA "Restu Ibu" Sragen from June to August 2020. The examination method used an automatic method with the Lenshooke SQA X1 PRO tool and a manual method with Papanicolaou staining. The results of the study, conformity test with WHO 2010 normal standards, automatic methods reached 94.4% compared to manual methods. The next statistical test was with standard mean, normal sperm morphology data had a significance of 0.001, abnormal sperm head data had a significance value of 0.956 and abnormal sperm tail data had a significance value of 0.339. The Lenshooke SQA XI PRO device based on automatic technology can be used in laboratory services for sperm analysis in addition to manual methods. Suggestions for using the Lenshooke XI PRO automatic tools are still accompanied by the manual method.
Co-Authors Dewi, Yulia Ratna Edy Purwanto Gunawan, Lucia Sincu Purwanto, Adhipireno Santoso Budi, Santoso Setiawan, Limijadi Edward Kurnia Sulijaya, Suyono Seso Wahyuningsih, Sandra Tri