Article Per Year (5 Year)
p-Index From 2021 - 2026
0.444
P-Index
This Author published in this journals
All Journal Pharmacon Journal of Pharmaceutical and Sciences.
Hossain, Md. Sanower
Muhammadiyah University Of Surakarta
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Rungia pectinata (Linn.) Nees: A Review of Phytochemical Analysis and Pharmacological Activities Forid, Md. Shaekh; Azuri, Muhammad Saupi bin; Wan Ishak, Wan Maznah; Hossain, Md. Sanower
Pharmacon: Jurnal Farmasi Indonesia Vol 21, Special Issue 1, 2024
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v21i0.23596

Abstract

Rungia pectinata L. is an herbaceous weed traditionally used for many years for various disease conditions. Nevertheless, these indigenous medical practices are frequently regarded as self-limiting, necessitating a thorough examination of their purported benefits. This review aims to consolidate existing scientific insights and identify domains requiring additional research. The literature was searched using the keyword "Rungia pectinata" OR "Comb Rungia" in well-known scientific databases, including PubMed, Web of Science, and Scopus, and relevant papers were selected for this review. The leaf juice is used as a cooling agent and to treat smallpox in children, reducing pain and swelling. A paste made from the fresh leaves blended with castor oil can heal tinea capitis, a scaly fungoid scalp infection. This plant has a rich tradition of use in treating different disease conditions, such as hepatitis, acute conjunctivitis, children's dyspepsia, dysentery, and lymphoid tuberculosis. Additionally, it exhibits diverse pharmacological activities like antipyretic, anti-inflammatory, diuretic, analgesic, antifungal, and antibacterial effects. This study found that it has secondary metabolites, such as amino acids, glycosides, phenolics, terpenes, phytosterols, tannins, flavonoids, and carbohydrates. Additionally, a total of 38 isolated compounds were identified in essential oils, with the dominant compounds being trans-phytol, hexahydrofarnesyl acetone, and isophytol. However, the phytochemical compositions varied depending on the type of extraction process. R. pectinata presents a promising avenue for medicinal exploration, deeply rooted in traditional practices. This review underscores the need for a more thorough investigation into its diverse therapeutic applications and encourages further research to unlock the plant's full potential.
Aktivitas Antibakteri Ekstrak Daun Mangga Sengir (Mangifera indica L. Kultivar Sengir) terhadap Staphylococcus aureus: Studi In vitro dan Molecular Docking Yusrin Haniyyah; Md. Sanower Hossain
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 3 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i3.1778

Abstract

The antibacterial potential of the underexplored Mangifera indica L. cultivar Sengir remains poorly understood. This study evaluated the antibacterial activity of Sengir mango leaf extract against Staphylococcus aureus using integrated in vitro and in silico approaches. Leaves were extracted by maceration with 70% ethanol. The extract contained 293.8 mg GAE/g extract of total phenolics and 34.8 mg QE/g extract of total flavonoids. Antibacterial activity was assessed using the disk diffusion method at extract concentrations of 40%, 60%, 80%, and 100%, corresponding to 488, 732, 976, and 1,220 mg/mL, respectively. Ampicillin and 10% DMSO served as the positive and negative control, respectively. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were also determined. For the in silico study, 60 M. indica phytochemicals from IMPPAT were screened using SwissADME and ProTox-III, and seven compounds were docked against penicillin-binding protein 2a (PBP2a; PDB ID: 4CJN) using PyRx. The extract produced concentration-dependent inhibition zones of 11.00–17.17 mm, whereas ampicillin produced a 34.50 mm inhibition zone and 10% DMSO showed no inhibition. MIC and MBC values were 48.87 and 73.20 mg/mL, respectively. Guaiol showed the lowest predicted binding energy (-7.0 kcal/mol), whereas PASS analysis identified Pogostol, Myrtenyl acetate, and Bicyclogermacrene as potential antibacterial compounds. Overall, Sengir mango leaf extract showed antibacterial activity against S. aureus, while computational analysis identified Guaiol and Pogostol as promising bioactive candidates for further validation.
Co-Authors Azuri, Muhammad Saupi bin Forid, Md. Shaekh Wan Ishak, Wan Maznah Yusrin Haniyyah