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All Journal Cerdika: Jurnal Ilmiah Indonesia Eduvest - Journal of Universal Studies
Priyanto, M. Hikmawan
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Aerospace Engineering Humanities Computer Science & IT Economics, Econometrics & Finance Education Health Professions Neuroscience Public Health Social Sciences

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Pansitopenia: Challenges Of Approach And Case Handling In Peripheral Hospitals Priyanto, M. Hikmawan; Mas’ud, Ibnu
Eduvest - Journal of Universal Studies Vol. 4 No. 10 (2024): Journal Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v4i10.43691

Abstract

Pancytopenia is a hematological condition characterized by a decrease in three blood cell lines: erythrocytes, leukocytes, and platelets. This condition is not an independent disease, but a manifestation of various underlying diseases. Pancytopenia can be caused by impaired blood cell production in the bone marrow or increased destruction of blood cells in the periphery. Precise and prompt identification of the etiology is essential, given that pancytopenia can be life-threatening if not treated properly. This study aims to analyze and identify the causes of pancytopenia in patients at Batang Regency Hospital, as well as provide recommendations for appropriate treatment based on the etiology found. The methods used were clinical observation, laboratory examination, and diagnostic imaging in a 58-year-old patient with the main complaint of weakness and a history of pancytopenia. The examination includes a complete blood count, a smear of peripheral blood, and a clinical evaluation. The results showed that the patient had central type pancytopenia, with a suspected etiology of aplastic anemia or myelodysplastic syndrome. Other differential diagnoses include vitamin B12 deficiency. Although a bone marrow biopsy is necessary to confirm the diagnosis, initial therapy with blood transfusions and nutritional improvements has shown an improvement in the patient's condition. The conclusion of this study is the importance of a thorough evaluation to identify the etiology of pancytopenia. Proper treatment should be based on the underlying cause, which will affect the prognosis and prevent recurrence. A comprehensive approach can improve patients' quality of life and reduce the risk of complications
Pansitopenia pada Riwayat Perdarahan Saluran Cerna Bagian Atas : Tantangan Pendekatan Kasus di RS Perifer Priyanto, M. Hikmawan; Mas’ud, Ibnu
Cerdika: Jurnal Ilmiah Indonesia Vol. 4 No. 11 (2024): Cerdika: Jurnal Ilmiah Indonesia
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/cerdika.v4i11.2156

Abstract

Pansitopenia adalah kondisi yang ditandai dengan penurunan ketiga jenis sel darah tepi: hemoglobin, trombosit, dan leukosit. Hemoglobin kurang dari 11,5 g/dL pada wanita dan 13,5 g/dL pada pria, trombosit kurang dari 150.000/ul, dan leukosit kurang dari 4000/ul menunjukkan kondisi ini. Pansitopenia bukan penyakit tersendiri, melainkan manifestasi dari kondisi lain seperti infeksi, autoimun, genetik, gizi buruk, atau keganasan. Penentuan penyebab pansitopenia penting untuk diagnosis dan pengobatan yang tepat. Penyebab bisa karena penurunan produksi sel atau peningkatan kerusakan sel. Dalam kasus seorang wanita 54 tahun yang dirawat dengan keluhan lemas dan riwayat BAB hitam serta muntah darah, pemeriksaan menunjukkan pansitopenia tipe sentral. Tidak ditemukan indikasi efek obat atau toksin, splenomegali, atau pembesaran limfa. Data laboratorium seperti hepatitis, HIV, fungsi hati, dan skrining autoimun tidak tersedia, sehingga dugaan pansitopenia disebabkan oleh anemia aplastik atau mielodisplasia. Pasien menerima terapi supportif termasuk transfusi darah dan antibiotik, tetapi memilih pulang sebelum pemeriksaan lebih lanjut. eval_uasi menyeluruh diperlukan untuk mengidentifikasi etiologi yang mendasari pansitopenia, yang berperan penting dalam menentukan penanganan dan prognosis pasien.
Co-Authors Mas’ud, Ibnu