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All Journal Jurnal Pharmacopoeia Preventif : Jurnal Kesehatan Masyarakat
Sultan, Dharma
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Medicine & Pharmacology Public Health

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Correlation Between Probiotic Use And Blood Pressure In Hypertensive Adults: A Cross-Sectional Study Sultan, Dharma; Setyawan, Yuswanto
Jurnal Pharmacopoeia Vol 4 No 2 (2025): September 2025
Publisher : Poltekkes Kemenkes Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33088/jp.v4i2.1081

Abstract

Hypertension remains a significant global health burden and is closely linked to cardiovascular morbidity. Emerging evidence suggests that gut microbiota plays an essential role in modulating blood pressure, particularly through the use of probiotics and prebiotics. This study investigated the relationship between the frequency of probiotic consumption and blood pressure control in patients with essential hypertension. A total of 100 hypertensive adults participated in this cross-sectional study, and data were collected through structured interviews, food frequency questionnaires, and blood pressure assessments. Statistical analyses included Chi-square and Spearman correlation tests. The results demonstrated a significant association between higher frequency of probiotic intake and better blood pressure control (p = 0.008), with a moderate negative correlation (r = –0.45) observed between intake duration and systolic blood pressure. Additionally, individuals who consumed both probiotics and prebiotic-rich foods exhibited enhanced blood pressure improvement. These findings support the potential of probiotic-prebiotic synergy in modulating gut microbiota to regulate blood pressure. The incorporation of prebiotics is essential, as they serve as substrates that stimulate the growth and activity of beneficial bacteria, thereby optimizing the efficacy of probiotic supplementation. The study highlights the practical implications of dietary interventions targeting the gut environment as a complementary strategy in hypertension management. Keywords: Hypertension, Probiotics, Prebiotics, Gut microbiota, Blood pressure
Association Between Patterns of Electronic Cigarette Use and Recurrent Bronchitis Among Young Adults Sultan, Dharma; Setyawan, Yuswanto
Preventif : Jurnal Kesehatan Masyarakat Vol. 16 No. 3 (2025): Preventif : Jurnal Kesehatan Masyarakat
Publisher : Tadulako University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/seswrj78

Abstract

Electronic cigarette use has become increasingly prevalent among young adults, raising concerns about its potential impact on respiratory health. This study aimed to investigate the association between patterns of electronic cigarette use and the occurrence of recurrent bronchitis symptoms in young adults. A quantitative analytic study with a cross-sectional approach was conducted involving 150 respondents aged 18–25 years. Participants were selected using purposive sampling, and data were collected through structured questionnaires. The variables measured included frequency of e-cigarette use and incidence of recurrent bronchitis symptoms. Data analysis involved Chi-square tests and Spearman correlation to examine the relationship between vaping patterns and respiratory complaints. The results showed a significant association between frequent e-cigarette use (≥4 times per week) and the presence of recurrent bronchitis symptoms, with a Spearman correlation value indicating a strong positive relationship. Regular users were found to be four times more likely to experience bronchitis than occasional or non-users. These findings suggest that habitual vaping may lead to bronchial irritation and inflammation, contributing to the onset of recurrent bronchitis. In conclusion, frequent electronic cigarette use poses a substantial risk to respiratory health among young adults and warrants greater public health attention.
Co-Authors Setyawan, Yuswanto