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All Journal Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
Widya, Andre C
Indonesian Socety of Obstetrics and Gynecology
Health Professions Medicine & Pharmacology Public Health

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The Role of Progesterone Induced Blocking Factor in Threatened Abortion Widya, Andre C; Loho, Maria F; Wantania, John J E
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 4, October 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (130.213 KB) | DOI: 10.32771/inajog.v5i4.557

Abstract

Objective: To determine the role of progesterone-induced blocking factor (PIBF) in women with threatened abortion. Methods: This was a cross-sectional study. The blood serum of two groups, the first one was women with normal gestation of  20 weeks, and the second one was those with imminent abortion in Prof. Dr. R.D. Kandou Hospital, and Subcenter Hospital in Manado, was collected. Samples were processed with PIBF ELISA-kit. Results: PIBF serum value of women in normal gestation  20 weeks is (47.15323.830)ng/ml and threatened abortion is (11.540 4.892) ng/ml, with p value = 0.000. Conclusion: PIBF serum value of women with threatened abortion is significantly lower compared to women of normal gestation  20 weeks. This study showed that PIBF has an important role in maintaining pregnancy and can be used as a biologic marker of a pathologic process in pregnancy.Keywords: early pregnancy, pregnancy immunology, progesteroneinducedblocking factor, threatened abortion
The Role of Progesterone Induced Blocking Factor in Threatened Abortion Widya, Andre C; Loho, Maria F; Wantania, John J E
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 4, October 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (130.213 KB) | DOI: 10.32771/inajog.v5i4.557

Abstract

Objective: To determine the role of progesterone-induced blocking factor (PIBF) in women with threatened abortion. Methods: This was a cross-sectional study. The blood serum of two groups, the first one was women with normal gestation of  20 weeks, and the second one was those with imminent abortion in Prof. Dr. R.D. Kandou Hospital, and Subcenter Hospital in Manado, was collected. Samples were processed with PIBF ELISA-kit. Results: PIBF serum value of women in normal gestation  20 weeks is (47.15323.830)ng/ml and threatened abortion is (11.540 4.892) ng/ml, with p value = 0.000. Conclusion: PIBF serum value of women with threatened abortion is significantly lower compared to women of normal gestation  20 weeks. This study showed that PIBF has an important role in maintaining pregnancy and can be used as a biologic marker of a pathologic process in pregnancy.Keywords: early pregnancy, pregnancy immunology, progesteroneinducedblocking factor, threatened abortion
Co-Authors Loho, Maria F Wantania, John J E