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All Journal Jurnal Ilmiah PANNMED (Pharmacist, Analyst, Nurse, Nutrition, Midwivery, Environment, Dentist)
Ice Ratnalela Siregar
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Health Professions Medicine & Pharmacology Nursing Public Health

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HUBUNGAN IgG DAN IgM DENGUE TERHADAP JUMLAH TROMBOSIT PADA PASIEN DEMAM BERDARAH DENGUE DI RUMAH SAKIT PENDIDIKAN PROF.dr.CHAIRUDDIN PANUSUNAN LUBIS UNIVERSITAS SUMATERA UTARA Ice Ratnalela Siregar; Muhammad Iqbal
Jurnal Ilmiah PANNMED (Pharmacist, Analyst, Nurse, Nutrition, Midwivery, Environment, Dentist) Vol. 19 No. 1 (2024): Vol. 19 No. 1 (2024): Jurnal Ilmiah PANNMED Periode Januari - April 2024
Publisher : Poltekkes Kemenkes Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36911/pannmed.v19i1.2084

Abstract

The immune responses that play a role in DHF cases are Immunoglobulin M (IgM) and Immunoglobulin G (IgG). In primary Dengue infection, IgM begins to form and is detected on the third to fifth day, whereas in secondary Dengue infection, IgG levels will increase and then remain in the human body with low titers for life. Thrombocytopenia occurs in DHF patients due to antigen-antibody reactions and activation of the complement system which causes deposition of IgM and IgG immune cells on the surface of platelet cells. This causes reticuloendothelial cells to destroy platelets so that DHF patients will experience thrombocytopenia. To find out the analysis of dengue IgG and IgM examination on the results of platelet counts in dengue hemorrhagic fever patients at Prof. Teaching Hospital. dr. Chairuddin Panusunan Lubis, University of North Sumatra. The research used is descriptive quantitative. The examination method used is Dengue IgG and IgM Dengue Rapid Test, Platelet Count Examination using a Hematology Analyzer. The number of respondents is 11 samples taken by total sampling technique. Based on the results of a study of Dengue IgG and IgM in Dengue Hemorrhagic Fever patients at Prof. Teaching Hospital. dr. Chairuddin Panusunan Lubis, University of North Sumatra who had IgG + and IgM levels - more, namely 10 (92%) patients, IgG - and IgM + as many as 1 (8%) patients. Based on the number of platelets obtained in Dengue Hemorrhagic Fever patients at Prof. Teaching Hospital. dr. Chairuddin Panusunan Lubisa, University of North Sumatra, which decreased by 9 patients, and there were some who had normal platelet counts of 2 patients. There is no relationship between Dengue IgG and IgM on platelet count in Dengue Hemorrhagic Fever patients.
RELATIONSHIP OF C-REACTIVE PROTEIN IN HYPERTENSION PATTIENTS IN JAVANESE AND MALAY TRIBES AT RAMBUNG COMMUNITY HEALTH CENTER, BINJAI CITY Ice Ratnalela Siregar; Shalsabila Zulkarnain
Jurnal Ilmiah PANNMED (Pharmacist, Analyst, Nurse, Nutrition, Midwivery, Environment, Dentist) Vol. 20 No. 1 (2025): Jurnal Ilmiah PANNMED Periode Januari - April 2025
Publisher : Poltekkes Kemenkes Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36911/pannmed.v20i1.2245

Abstract

C-reactive protein is a natural inflammation marker produced by the body when the body experiences inflammation or infection. Hypertension is known to be one of the diseases associated with the risk of cardiovascular disease which can trigger the production of this acute phase protein in the body so that its concentration increases and can be detected by qualitative laboratory examination. Hypertension is influenced by age factors, as age increases, a person is more susceptible to hypertension, therefore those aged 60 years and over or the elderly are very susceptible to this disease. In addition, differences in ethnicity cause differences in customs, culture, and eating habits, it is known that hypertension is a common disease experienced by the Malay Tribe than the Javanese Tribe. Therefore, this study was conducted with the aim of determining the relationship between C-reactive protein in elderly hypertension patients along with a description of the results of C-reactive protein in the differences between the Javanese and Malay Tribes. This type of research used a quantitative descriptive method with sampling using a purposive sample technique. Data processed using Fisher Exact Test analysis and CRP examination carried out using the agglutination method. This study was conducted for one week starting from April 29th to May 4th, 2024 with a sample obtained of 45 samples (total population). Based on the research conducted, the positive CRP results were 4 with 1 coming from the Javanese tribe and 3 from the Malay tribe and there was no significant relationship with the Exact Sig value. (2-Sided) 0.558>0.05.
Co-Authors Muhammad Iqbal Shalsabila Zulkarnain