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All Journal Jurnal Farmasi Medica (Pharmacy Medical Journal) PMJ Jurnal Lentera: Penelitian dan Pengabdian Masyarakat
Sumantri Abdullah, Surya
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Other

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Physicochemical Profile of Red Ginger (Zingiber officinale) SNEDDS as Potential Antidiabetic Sumantri Abdullah, Surya; Sudewi, Sri; Antasionasti, Irma; Rezky Putri Indarwati Abdullah
Jurnal Farmasi Medica/Pharmacy Medical Journal (PMJ) Vol. 8 No. 2 (2025): Jurnal Farmasi Medica
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pmj.v8i2.64731

Abstract

This study developed a Self-Nanoemulsifying Drug Delivery System (SNEDDS) of red ginger (Zingiber officinale var. rubrum) to enhance its stability and bioavailability. 8 formulations (F1–F8) were tested with varying Tween 80 : PEG 400 ratios (Smix 4.5 mL). Formula F7 (2.8 : 1.8 mL) produced a water-clear emulsion with pH 5.20 ± 0.02 and excellent stability for 28 days. PSA results showed droplet size 20.33 ± 0.57 nm, PDI 0.430 ± 0.053, and zeta potential −19.58 ± 1.50 mV. These findings indicated that F7 is the optimum, physicochemically stable SNEDDS formulation, potentially improving solubility and oral bioavailability of red ginger’s active compounds as a phytopharmaceutical antidiabetic candidate Keywords: red ginger, SNEDDS, nanoemulsion, physicochemical stability
PKM Pelatihan dan Pendampingan Produksi Minyak Gosok Alami Pala di Pondok Pesantren dan Panti Asuhan Sumantri Abdullah, Surya; Antasionasti, Irma; Ahmad, Musfirah; Jayanto, Imam
Jurnal Lentera: Penelitian dan Pengabdian Masyarakat Vol. 6 No. 2 (2025): Jurnal Lentera: Penelitian dan Pengabdian Masyarakat
Publisher : Yayasan Bina Lentera Insan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57207/ahb26w44

Abstract

Herbal rubbing oil is a widely used traditional remedy for relieving muscle pain, improving blood circulation, and promoting relaxation. Nutmeg (Myristica fragrans) contains several bioactive compounds such as myristicin, safrole, eugenol, and elemicin, which possess analgesic and anti-inflammatory properties, making it suitable for development into a natural rubbing oil product. However, the utilization of nutmeg oil as an economically valuable herbal product remains underdeveloped, particularly in Islamic boarding schools and orphanages, where practical skills and entrepreneurial knowledge are highly needed. This Community Service Program (PKM) aimed to provide training and assistance in producing nutmeg-based rubbing oil through educational sessions, demonstrations, and hands-on practice. The results indicate a significant improvement in participants’ knowledge regarding the benefits of nutmeg and the safe use of herbal remedies, as well as an enhancement in technical skills related to production, packaging, and understanding product economic value. Participants successfully produced stable nutmeg rubbing oil with a distinct aromatic profile. The program positively contributed to improving health independence and promoting micro-entrepreneurship based on natural herbal products. This initiative demonstrates strong potential to be replicated in similar institutions as a model for local resource–based economic empowerment.  
Co-Authors Abdullah, Rezky Putri Indarwati Ahmad, Musfirah Antasionasti, Irma Jayanto, Imam Sri Sudewi, Sri