<![CDATA[Abstract: Hypercholesterolemia is one of the abnormalities that occur in the body's metabolism, which is shown to cause an increase in total cholesterol levels exceeding the normal limit, which is 200 mg/dL. Metabolic disorders can increase blood fat levels due to enzyme deficiencies, LDL receptor abnormalities, and genetic factors that trigger excess cholesterol production or decrease cholesterol clearance by the liver. Natural ingredients of fruit can help reduce body fat levels. Yali pears contain compounds such as carotenoids, chlorophyll, triterpenoids, polyphenols, fibre, and vitamin C that can help improve blood lipid profiles. This study looked at the effect of giving Yali pear juice on total cholesterol levels in the blood, so that it can be one of the natural additional treatments for hypercholesterolemia patients. This study uses a non-equivalent control group design, namely research conducted with a pre- and posttest, which is divided into two groups, namely the treatment group given Yali pear juice and the control group given a placebo. Yali pear juice and a placebo were given for 10 days. Checking total cholesterol levels in the blood using GCU easy touch tools before and after the study. Data analysis using the T-test parametric test. Analysis of pre-test data with the post-test of the treatment group obtained a result of p0.05, which means that there is an effect of Yali pear juice on total cholesterol levels in the blood. In the pre-test with the post-test, the control group had p0.05, which means there was no placebo effect on total cholesterol levels in the blood. Giving Yali pear juice for 10 days has an effect on reducing total cholesterol levels in the blood.]]>
