Jamshidovna , Yokubova Nilufar
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EVALUATING THE SHELF LIFE OF ESCIN Obitovich , Tursunov Khurshid; Jamshidovna , Yokubova Nilufar
Journal of Higher Education and Academic Advancement Vol. 1 No. 7 (2024): Journal of Higher Education and Academic Advancement
Publisher : PT. Antis International Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/ejheaa.v1i7.786

Abstract

The determination of drug shelf life is vital for ensuring quality and stability, considering factors such as extraction, storage, transportation, and others to establish ideal storage conditions and expiration dates. While standard stability tests follow industry guidelines, the unique challenges posed by conducting accelerated tests for some temperature-sensitive drugs, such as herbal medicines, necessitate reliance on natural (continuous) tests as the primary method for determining stability. Positive results from accelerated tests may indicate that stability can be maintained despite short-term deviations under normal storage conditions. Consequently, real-time continuous testing plays a pivotal role in determining and validating the optimal shelf life following drug registration, simulating actual storage conditions during circulation. In light of these considerations, the shelf life of Escin was determined only through natural testing
ASSESSING THE STABILITY OF ESCIN Jamshidovna , Yokubova Nilufar
Journal of Higher Education and Academic Advancement Vol. 1 No. 7 (2024): Journal of Higher Education and Academic Advancement
Publisher : PT. Antis International Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/ejheaa.v1i7.787

Abstract

Drug quality and stability are intricately linked, with temperature, light, and humidity playing crucial roles in their preservation. It is imperative for pharmacy experts to ascertain the shelf life of drugs by studying various factors such as extraction, storage, transportation, and more to establish ideal storage conditions and expiration dates. While standard stability tests are conducted based on industry guidelines, conducting accelerated tests for certain temperature-sensitive drugs, particularly herbal medicines, presents challenges. As a result, natural (continuous) tests are relied upon as the primary method for determining stability. Based on these considerations, the shelf life of Escin was determined solely through natural testing