Festy Ladyani
Faculty of Medicine, Malahayati University Bandar Lampung, Indonesia

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Integrating Gastrointestinal and Dental Management in Analgesic-Associated Dyspepsia Festy Ladyani; Indramayanti Warganegara; Ida Fitriyani; Wiwin Wildaniatul Janah; Yogi Dwi Praja Saputra; Yuli Tri Purnamasari; Zada Damar Pasa; Miftha Nazsiroh
Biomedical Research and Theory Letters Vol. 1 No. 1 (2025): Biomedical Research and Theory Letters
Publisher : CV. FOUNDAE

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58524/brtl.v1i1.65

Abstract

Dyspepsia is a prevalent gastrointestinal disorder that manifests as epigastric pain, nausea, bloating, postprandial discomfort, and burning sensations in the upper abdomen, often triggered by irregular eating patterns, stress, or the consumption of irritant foods and beverages such as coffee, spicy meals, and fatty products, but it can also be induced by prolonged use of non‑steroidal anti‑inflammatory drugs (NSAIDs). In Indonesia, self‑medication with analgesics remains widespread, yet its impact on dyspepsia in primary care settings is rarely documented, making this study relevant to highlight the clinical features and therapeutic management of drug‑induced dyspepsia. A 39‑year‑old woman presented to Way Halim II Primary Health Center in Bandar Lampung with persistent nausea, vomiting, epigastric pain, bloating, and retrosternal burning after consuming sodium diclofenac daily for three months to relieve untreated dental pain, combined with frequent coffee intake. Endoscopic and laboratory findings were normal, while dental radiography revealed an impacted molar, indicating the underlying source of chronic analgesic use. Clinical data were obtained through anamnesis, physical examination, laboratory evaluation, and imaging, and management consisted of proton pump inhibitor therapy (omeprazole 20 mg), prokinetic agents (domperidone 10 mg), and lifestyle modification, including avoidance of dietary triggers. The patient was advised to undergo dental extraction to eliminate the primary cause of analgesic dependence but declined due to procedural anxiety. Following therapy, symptoms improved significantly, with reduced nausea and epigastric discomfort, demonstrating the effectiveness of pharmacological intervention combined with behavioral modification. This study emphasizes the novelty of identifying dyspepsia linked to prolonged unsupervised NSAID use in a primary care context, underscoring the importance of early recognition of drug‑induced gastrointestinal disorders, patient education on the risks of self‑medication, and multidisciplinary management that integrates gastrointestinal and dental care. Such an approach is critical to prevent recurrence, improve patient outcomes, and strengthen primary health care responses to common but neglected conditions in resource‑limited settings.
Clinical Management and Lifestyle Intervention for Hypertension in an Elderly Patient at a Primary Health Care Facility in Indonesia Festy Ladyani; Susi; Yustira Mayasari; Welvin Kurniawan Susanto; Widi Anggaraini; Widya Karina Sari; Wijihan Rusi Nur Aulia; Windy Septrihani; Mikael Syväjärvi
Biomedical Research and Theory Letters Vol. 2 No. 1 (2026): Biomedical Research and Theory Letters
Publisher : CV. FOUNDAE

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58524/brtl.v2i1.82

Abstract

Hypertension remains one of the most prevalent chronic non-communicable diseases worldwide and constitutes a major risk factor for cardiovascular morbidity and mortality, particularly among elderly populations. Despite the availability of effective antihypertensive therapies, blood pressure control remains suboptimal in many patients due to delayed diagnosis, inadequate treatment adherence, and unhealthy lifestyle practices. Primary health care facilities play a critical role in the early detection, management, and long-term monitoring of hypertension, especially in low- and middle-income settings. This study describes the clinical management and outcomes of an elderly patient with poorly controlled hypertension treated at a community-based primary health care center in Bandar Lampung, Indonesia. A 70-year-old woman presented with persistent headaches, dizziness, and fatigue lasting for approximately two weeks. Initial clinical assessment revealed elevated blood pressure of 170/90 mmHg. The patient had a five-year history of hypertension but reported inconsistent use of antihypertensive medication and suboptimal lifestyle behaviors, including frequent caffeine consumption and limited physical activity. Management involved pharmacological therapy using amlodipine at a daily dose of 5 mg, combined with comprehensive non-pharmacological interventions. The patient received individualized counseling focused on lifestyle modification, including dietary salt restriction, reduction of caffeine intake, encouragement of regular physical activity, and routine blood pressure monitoring. Emphasis was also placed on improving medication adherence through patient education and follow-up support. At a two-week follow-up evaluation, the patient demonstrated a clinically meaningful reduction in blood pressure to 150/80 mmHg, accompanied by a marked improvement in reported symptoms. Additionally, the patient showed enhanced understanding of hypertension management and greater adherence to dietary and lifestyle recommendations. These findings underscore the importance of integrated hypertension management strategies in primary care settings, particularly for elderly patients. The combination of appropriate pharmacological treatment, lifestyle modification, and patient education can significantly improve blood pressure control and reduce the risk of long-term complications. Strengthening primary care–based hypertension programs may contribute to better cardiovascular health outcomes at the community level.