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All Journal Buletin Veteriner Udayana
Yousef Haig Setrak Babikian
Rhea Natural Sciences, Jl. HR Rasuna Said Kav. H1-H2, Kuningan, Setiabudi, South Jakarta, Indonesia, 12920
Immunology & microbiology Public Health Veterinary

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THE EFFECT OF NATURAL GUARD ADMINISTRATION IN DRINKING WATER ON ND-ANTIBODY TITERS IN BROILERS Made Shanty Meidiana; Ida Bagus Komang Ardana; Anak Agung Gde Oka Dharmayudha; I Made Merdana; Luh Made Sudimartini; Yousef Haig Setrak Babikian; Haig Yousef Babikian; Rubiyanto Widodo Haliman; Theng In Yen; Kristina; Hendi Yanto Efendy
Buletin Veteriner Udayana Bul. Vet. Udayana. February 2024 Vol. 16 No. 1
Publisher : Fakultas Kedokteran Hewan Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/bvu.v16i1.49

Abstract

The broiler is the largest sector producing protein sources in Indonesia. Poultry farms are susceptible to viral diseases, including the Newcastle Disease Virus (NDV). Viral diseases can be prevented by vaccination to increase antibody titters in broiler chickens. Induction of antibody titters can be increased by providing additional ingredients such as immune system stimulants known as immunomodulators. One material that can be used as an immunomodulator is the NATURALGUARD (NG). This research was conducted to determine the effect of NG supplementation in drinking water on ND antibody titters in broilers. This study used a completely randomized design with four treatments, namely P0 as a control without NG treatment, and P1, P2, and P3 were given NG treatment at doses of 1, 2, and 4 g/L, respectively adlibitum for 30 days starting at three days of age. Blood samples were taken on day one before treatment, 15 and 30 days after treatment for the hemagglutination inhibition (HI) test. The results showed that maternal antibodies against ND on the first day were protective but not uniform; the highest mean HI 4 log 2 titter was at P0 (512 ± 280.43) and the lowest at P2 (384 ± 140.21). The decrease in antibodies occurred at the age of 18 days to the highest at P0 and P3, namely 16 ± 0, and the highest at P2 (16.66 ± 4.13), and at the age of 33 days, the lowest titter was at P1 (4 ± 0) and the highest was at P2 and P3 (10±6.57). It can be concluded that NATURALGUARD supplementation shows an immunomodulating effect in broiler chickens that have not been re-vaccinated with Newcastle Disease through a slower regulation of decreasing antibody titters at NG supplementation doses of 2 and 4 g/L.
THE EFFECT OF GIVING NATURAL GUARD ESSENTIAL OIL IN DRINKING WATER ON BLOOD UREA NITROGEN LEVELS, CREATININE, AND AMINOTRANSFERASE IN BROILERS Muhamad Abdul Shidiq; Ida Bagus Komang Ardana; I Ketut Sumadi; I Made Merdana; Luh Made Sudimartini; Yousef Haig Setrak Babikian; Haig Yousef Babikian; Rubiyanto Widodo Haliman; Kristina; Theng In Yen; Hendi Yanto Efendy
Buletin Veteriner Udayana Bul. Vet. Udayana. February 2024 Vol. 16 No. 1
Publisher : Fakultas Kedokteran Hewan Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/bvu.v16i1.66

Abstract

To increase growth and feed efficiency, we can use feed additives through feed or drinking water, one of which is the use of essential oils. NATURALGUARD is  a mixture of natural oils, namely pine oil (Pinus sp.), lavender (Lavandula sp.), and eucalyptus oil (Eucalyptus sp.) which contains active compounds as immunomodulators, antibacterials, antioxidants, anti-inflammatory, antifungal and antiviral. This study aims to determine the level of Blood Urea Nitrogen (BUN), Creatinine, Aspartate Aminotransferase (AST), and Alanine Aminotransferase (ALT) in broilers after being given NATURALGUARD via drinking water. This study used a completely randomized design with a total sample of 24 broiler CP-707 strain, with four treatments and six replications. The treatment applied was P0 as a control without giving NATURALGUARD, P1 P2, and P3 were given NATURALGUARD at doses of 1, 2, and 4 g/L respectively, adlibitum for 30 days. At the end of the study, 3 mL of blood sample was taken via the pectoral vein aseptically, and then a blood serum examination was carried out. The research results showed that the highest mean BUN level was at P0 (8.9 mg/dL) and the lowest was at P1 (5.2 mg/dL), the highest creatinine was at P3 (1.08 mg/dL) and the lowest was at P0 and P1 (1, 0 mg/dL), AST was highest at P0 (273 µ/L) and lowest at P2 (220 µ/L), and ALT was highest at P0 (7.5 µ/L) and lowest at P3 (5.48 µ/ L). Statistical results showed no significant differences in BUN, creatinine, AST, and ALT levels in all treatment groups. It was concluded that NATURALGUARD as feed additive at doses of 1, 2, and 4 g/L via drinking water is safe to be used in broilers.
Co-Authors Anak Agung Gde Oka Dharmayudha Haig Yousef Babikian Hendi Yanto Efendy I Ketut Sumadi I Made Merdana I Made Merdana Ida Bagus Komang Ardana Ida Bagus Komang Ardana Kristina Luh Made Sudimartini Luh Made Sudimartini Made Shanty Meidiana Muhamad Abdul Shidiq Rubiyanto Widodo Haliman Theng In Yen