I Wayan Sudira
Laboratorium Farmakologi dan Farmasi Veteriner, Fakultas Kedokteran Hewan, Universitas Udayana, Jl. P.B Sudirman, Denpasar, Bali, Indonesia

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EFFICACY OF ALBENDAZOLE AGAINST PARAMPHISTOMUM SP. INFECTIONS IN BALI CATTLE IN BALI Ni Komang Sri Ratih; I Wayan Sudira; I Made Dwinata
Buletin Veteriner Udayana Bul. Vet. Udayana. August 2025 Vol. 17 No. 4
Publisher : Fakultas Kedokteran Hewan Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/bulvet.2025.v17.i04.p23

Abstract

Paramphistomosis, caused by the trematode Paramphistomum sp., is a prevalent parasitic disease affecting Bali cattle that leads to significant health issues and productivity losses. This study evaluated the anthelmintic efficacy of albendazole (10 mg/kg BW) against Paramphistomum sp. infections in Bali cattle through fecal egg count reduction. Using a one-group pretest-posttest design, we examined 20 naturally infected Bali cattle (aged 6 months-2 years) from three locations in Bali (Bangli Regency, Badung Regency, and Denpasar City). Fecal samples were collected on day 0 (pretreatment), day 7, and day 14 post-treatment and analyzed using the Whitlock sedimentation method. The Fecal Egg Count Reduction Test (FECRT) and Paired Sample T-test were employed for data analysis. Results demonstrated a statistically significant reduction (p<0.05) in egg counts post-treatment, with FECRT reaching 87.80% by day 14. These findings indicate that albendazole is effective against Paramphistomum sp. infections in Bali cattle, supporting its use in control programs.