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All Journal Jurnal Kesehatan Saintika Meditory Jurnal Ilmu Kesehatan Indonesia (JIKSI)
Novia, Juvita
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Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Sindrom Hipoventilasi Obesitas (Pickwickian Syndrome): Laporan Kasus Novia, Juvita; Ida Bagus, Aditya Nugraha; Wira, Gotera
Jurnal Ilmu Kesehatan Indonesia Vol. 6 No. 4 (2025): Desember 2025
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v6i4.1623

Abstract

Background: Obesity hypoventilation syndrome (OHS) or Pickwickian syndrome is a chronic respiratory disorder characterized by the combination of obesity, daytime hypercapnia, and sleep-related breathing disturbances. This condition is often underdiagnosed and may increase the risk of morbidity and mortality. Case: A 30-year-old male presented with complaints of shortness of breath, snoring during sleep, frequent nighttime awakenings, fatigue, and headaches. The patient was severely obese and had a history of hypertension, type 2 diabetes mellitus, and a 15-year history of smoking one pack of cigarettes daily. He was diagnosed with severe community-acquired pneumonia (CAP) with sepsis, right heart failure, and OHS. The patient received ventilatory support, diuretics, antibiotics, blood glucose regulation with insulin, and physiotherapy. Discussion: During hospitalization, the patient had difficulty weaning from the ventilator due to OHS. The diagnosis was based on three main criteria: a body mass index >30 kg/m², daytime PaCO₂ >45 mmHg, and sleep-disordered breathing in the absence of other causes of alveolar hypoventilation. Conclusion: OHS should be promptly recognized and managed through a multidisciplinary approach to reduce morbidity and mortality. Education and clinical awareness of this syndrome must be improved, as it is frequently underdiagnosed. Keywords: obesity, hypoventilation, pickwickian syndrome, sleep disorder
Karakteristik Pasien Nodul Tiroid di RS Ngoerah Denpasar Novia, Juvita; Gotera, Wira; Nugraha, Ida Bagus Aditya
Jurnal Kesehatan Saintika Meditory Vol 8, No 2 (2025): November 2025
Publisher : STIKES Syedza Saintika Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30633/jsm.v8i2.30627

Abstract

Thyroid nodules are the most common endocrine neoplasia seen in the clinic. The prevalence of thyroid nodules increases with age, sex, history of radiation exposure, family history, and other factors. The purpose of this study was to determine the prevalence and characteristics of patient with thyroid nodule at Ngoerah Hospital based on laboratory, ultrasonography and histopathology. This descriptive observational study involved 40 subjects. Data were obtained from the medical records of outpatient thyroid nodules who visited the Diabetes Polyclinic and inpatients at Ngoerah Hospital. The data collection was carried out within 3 months, from 1 December 2022 until 28 February 2023. The subjects consisted of 6 males (15%) and 34 females (85%), average age was 48 years and average nodule size was 3.9 cm. Thyroid hormone function was found most in 30 subjects (75%) euthyroid. Ultrasound using Ti-RADS score classification, 14 subjects were moderately suspicious (35%) and the same percentage for not suspicious group. FNAB using Bethesda classification, majority 23 subjects (57.5%) were benign. Histopathological showed 21 subjects (52.5%) were adenomatous struma. The highest proportion according to hormone function was euthyroid, moderately suspicious and not suspicious based on ultrasonography, nodule was benign based on FNAB, and adenomatous struma based on histopathology.
Co-Authors Ida Bagus Aditya Nugraha Ida Bagus, Aditya Nugraha Wira Gotera Wira, Gotera