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All Journal Indonesian Journal of Case Reports
Tan, Seu Kean
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Health Professions Medicine & Pharmacology Neuroscience Public Health

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Regeneration of the Anterior Talofibular Ligament Following PRP Therapy: A Case Report with Serial MRI Evidence See, Zhi Huang; Low, Sing Wei; Tan, Seu Kean
Indonesian Journal of Case Reports Vol. 3 No. 2 (2025): December 2025
Publisher : Heca Sentra Analitika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60084/ijcr.v3i2.352

Abstract

Lateral ankle sprain (LAS) is one of the most common lower limb injuries, particularly in individuals involved in sports and recreational activities. The anterior talofibular ligament (ATFL) is the structure most frequently affected. Platelet-rich plasma (PRP) has shown potential in promoting tissue regeneration and accelerating healing. We report a case of a grade 3 ATFL tear treated with a single PRP injection combined with functional rehabilitation therapy, with serial MRI scans demonstrating ligament continuity and clinical recovery. This case highlights PRP hypothesized as a useful adjunct treatment for LAS involving ATFL injury when combined with functional rehabilitation, as it may promote ligamentous healing, improve short-term symptoms, and potentially reduce the long-term risk of developing chronic ankle instability.
Co-Authors Low, Sing Wei See, Zhi Huang