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LABORATORY EXAMINATION OF HEMOLYTIC DISEASE IN NEONATES DUE TO RHESUS INCOMPATIBILITY Danny Ernest Jonas Luhulima; Christian Ronald Tanggo; Ria Amelia
Journal of Innovation Research and Knowledge Vol. 5 No. 8 (2026): Januari 2026
Publisher : Bajang Institute

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Abstract

Hemolytic disease of the newborn (HDN) occurs when fetal red blood cells (RBCs), which possess an antigen that the mother lacks, cross the placenta into the maternal circulation, where they stimulate antibody production. The antibodies return to the fetal circulation and result in RBC destruction. Three classifications of HDN are: ABO, other causes like unexpected immune antibodies like anti-c or anti-K and Rhesus–anti D alone or may be accompanied by other Rh antibodies, examples anti-D with anti-C or anti-E. Clinical presentation of HDN varies from mild jaundice and anemia to hydrops fetalis (with ascites, pleural and pericardial effusions). This article discusses hemolytic due to incompability Rhesus anti-D.)
Characteristics And Comorbidities In Patients With Urinary Tract Infections (UTI) Christian Ronald Tanggo; Kezia Desideria Bontong; Jumaini Andriana Sihombing
International Journal of Health Engineering and Technology Vol. 4 No. 6 (2026): IJHET MARCH 2026
Publisher : CV. AFDIFAL MAJU BERKAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55227/ijhet.v4i6.683

Abstract

Urinary tract infection (UTI) is a common urogenital infection in both community and hospital settings, most frequently caused by Escherichia coli. In Indonesia, UTIs are estimated to reach 90–100 cases per 100,000 population annually and occur more often in females due to a shorter urethra that facilitates microbial entry. This study aimed to describe UTI case characteristics by age, sex, hypertension, diabetes mellitus, recurrent UTI history, and clinical manifestations at Universitas Kristen Indonesia Hospital during 2020–2021. A descriptive design was applied using secondary data from medical records. A total of 102 patients met the inclusion and exclusion criteria. The highest proportion of cases occurred in the 22–59-year age group (53 patients; 52.0%). Female patients predominated (62; 60.8%). Hypertension was identified in 45 patients (44.1%) and diabetes mellitus in 25 (24.5%). Recurrent UTIs were found in 53 patients (52.0%). Dysuria was the most frequent clinical manifestation (81; 79.4%). These findings indicate that UTIs at this hospital mostly affected adult females and were commonly accompanied by hypertension and recurrent infection, with dysuria as the leading symptom.