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All Journal Lontara Journal Of Health Science And Technology
Anwar, Alvionita B.
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Chemistry Engineering Environmental Science Health Professions Medicine & Pharmacology

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Manajemen Klinis Tuberkulosis Paru Resistan Obat pada Lansia: Studi Kasus di Instalasi Rawat Inap RSUD Prof. Dr. Aloei Saboe Papeo, Dizky R.; Aulia, Tita Arikah; Husain, Siti Dinarti; Selviana, Selviana; Pangaribuan, Jhuandaniel Piator; Anwar, Alvionita B.
Lontara Journal of Health Science and Technology Vol. 7 No. 1 (2026): Januari-Juni 2026
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Politeknik Muhammadiyah Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53861/lontarariset.v7i1.644

Abstract

Drug-resistant pulmonary tuberculosis (DR-TB) is a challenging form of TB characterized by resistance to at least rifampicin and isoniazid, requiring the use of complex second-line therapies. This condition is often accompanied by complications that further aggravate the clinical course. The aim of this study was to evaluate the management of DR-TB with complications. This retrospective case study was based on the medical record of a 63-year-old female patient with a history of TB in 2020 who was diagnosed with relapsed DR-TB complicated by hypertension, anemia, and insomnia. The diagnosis was confirmed through a rapid molecular test showing a positive result for Mycobacterium tuberculosis with rifampicin resistance. Initial management included the administration of second-line antibiotics, blood transfusion to address anemia, and supportive care for accompanying symptoms. Following two consecutive positive results, the patient commenced second-line anti-tuberculosis (ATT) therapy according to MDR-TB treatment standards. Evaluation revealed improvement in hemoglobin levels after transfusion, although shortness of breath persisted and required further monitoring. In conclusion, the management of DR-TB with complications requires a multidisciplinary approach tailored to the patient’s clinical condition
Co-Authors Aulia, Tita Arikah Husain, Siti Dinarti Pangaribuan, Jhuandaniel Piator Papeo, Dizky R. Selviana Selviana