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All Journal Jurnal Riset Rumpun Ilmu Kesehatan (JURRIKES)
Diana Shintawati Purwanto
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Health Professions Medicine & Pharmacology Nursing Public Health

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Hubungan Kadar Kreatinin Darah dengan Tekanan Darah pada Pasien Penyakit Ginjal Kronik Dengan Hipertensi di RSUD ODSK Provinsi Sulawesi Utara Ivanna Delicia Barends; Diana Shintawati Purwanto; Youla Annatje Assa
JURNAL RISET RUMPUN ILMU KESEHATAN Vol. 5 No. 1 (2026): April: Jurnal Riset Rumpun Ilmu Kesehatan
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrikes.v5i1.7995

Abstract

Chronic Kidney Disease (CKD) is a global health problem with a continuously increasing prevalence and mortality rate. Global data indicates that kidney disorders have affected more than 850 million people, with CKD being one of the leading causes of death. North Sulawesi is recorded as one of the provinces with the highest prevalence of CKD. Blood creatinine is used as the primary marker of kidney function, while hypertension is a comorbidity commonly found in CKD patients and can act as both a cause and a consequence of impaired kidney function. Several studies have reported varying results regarding the relationship between creatinine levels and blood pressure. Purpose to analyze the association between serum creatinine levels and blood pressure in chronic kidney disease patients with hypertension at ODSK Hospital, North Sulawesi Province. Methods the research design used an observational analytic cross-sectional design. This study used an observational analytic cross-sectional design. It was a retrospective study utilizing secondary data from medical records for the period of June 2022 to August 2025. Total sampling method was employed with a sample size of 65 patients who met the inclusion criteria. Based on the Spearman correlation test results, the significance values between creatinine and systolic pressure was 0.685, and between creatinine and diastolic pressure was 0.787 (p-value >0.05). There is no significant correlation between serum creatinine levels and blood pressure in chronic kidney disease patients with hypertension at ODSK Hospital, North Sulawesi Province.
Hubungan Antara Red Blood Cell Distribution Width dengan Nilai Estimated Glomerular Filtration Rate Pasien Penyakit Ginjal Kronik di RSUD ODSK Provinsi Sulawesi Utara Juni Sarah Devi Sinambela; Murniati Tiho; Diana Shintawati Purwanto
JURNAL RISET RUMPUN ILMU KESEHATAN Vol. 5 No. 1 (2026): April: Jurnal Riset Rumpun Ilmu Kesehatan
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrikes.v5i1.8089

Abstract

Chronic kidney disease (CKD) is a global health problem with continuously increasing prevalence and mortality. This condition is characterized by a progressive and irreversible decline in kidney function, which is clinically assessed using the estimated glomerular filtration rate (eGFR) as one of the main parameters for staging and monitoring disease progression. Red blood cell distribution width (RDW) is a hematological parameter that reflects the degree of variation in erythrocyte size. In patients with CKD, elevated RDW levels are often associated with oxidative stress and chronic inflammation, which may accelerate kidney damage and increase mortality risk. To analyze the correlation between RDW and eGFR values in patients with chronic kidney disease at ODSK Hospital, North Sulawesi Province. This study used an analytical observational design with a cross‑sectional approach. It was conducted retrospectively using secondary data from the medical records of CKD patients at ODSK Hospital, North Sulawesi Province, from February 2024 to August 2025. This study used a total sampling method with 189 CKD patients who met the inclusion and exclusion criteria.  Based on Spearman-rank correlation analysis, the p‑value obtained was 0.129 (>0.05). There was no significant relationship between RDW and eGFR values in CKD patients at ODSK Hospital, North Sulawesi.Province.
Hubungan Kadar HbA1c dengan Kadar Kreatinin Darah pada Pasien Diabetes Melitus Tipe 2 di RSUD ODSK Provinsi Sulawesi Utara Aurelia Putri Valencia Gawendaleng; Diana Shintawati Purwanto; Murniati Tiho
JURNAL RISET RUMPUN ILMU KESEHATAN Vol. 5 No. 1 (2026): April: Jurnal Riset Rumpun Ilmu Kesehatan
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrikes.v5i1.8090

Abstract

Diabetes mellitus (DM) is a global health problem characterized by increased blood glucose levels. Type 2 diabetes mellitus (T2DM) accounts for 90-95% of all diabetes cases and is characterized by insulin resistance. Persistent hyperglycemia in patients with T2DM increases the risk of various complications, including renal dysfunction. Therefore, monitoring HbA1c levels is important for assessing long-term glycemic control and preventing complications, one of which is impaired kidney function that can be detected through increased blood creatinine levels. To analyze the relationship between HbA1c levels and blood creatinine levels in type 2 diabetes mellitus patients at RSUD ODSK North Sulawesi Province. This study used an observational analytic design with a cross-sectional approach. This study was retrospective using secondary data in the form of medical record data for the period February 2024-August 2025. This study used a total sampling method with 71 patients who met the inclusion criteria. The findings showed that the majority of patients had HbA1c levels >6,5%, while most blood creatinine levels were within the normal range. Based on the results of the Spearman-Rank correlation test, a significance value of 0.040 (p-value <0.05) was obtained. There is a significant relationship between HbA1c levels and blood creatinine levels, with a negative correlation strength in patients with type 2 diabetes mellitus at RSUD ODSK North Sulawesi Province.
Co-Authors Aurelia Putri Valencia Gawendaleng Ivanna Delicia Barends Juni Sarah Devi Sinambela Murniati Tiho Youla Annatje Assa