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All Journal Jurnal Kedokteran Diponegoro
Santoso Jaeri
Department of Medical Biology and Biochemistry, Faculty of Medicine Universitas Diponegoro, Semarang
Medicine & Pharmacology

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Characteristics of Intracerebral Hemorrhage at Dr. Kariadi General Hospital: A Serial Case Nadhira Faizah Putri Priambodo; Kayana Zahra Kallista Rambey; Amira Cinta Maharani; Diah Satyaningrum; Nuzulur Rakhmah Nurulyana; Gibran Chandra Syarif Hidayatullah; Maria Belladonna Rahmawati Sugianto; Santoso Jaeri
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 13, No 6 (2024): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v13i6.45097

Abstract

Background: Stroke is an acute neurological deficit caused by sudden or rapid disruption of blood circulation to the brain. Intracerebral hemorrhage is the subtype of stroke with the highest mortality and disability rate. Several risk factors may be related to the clinical outcome of intracerebral hemorrhage. Herewith we present a case series regarding the characteristics of intracerebral hemorrhage. Methods: A case series among three intracerebral hemorrhage cases in January - February 2024 at Dr. Kariadi Hospital. Epidemiological, and clinical data were recorded and reported. Case Presentations: Three cases were studied, the main complaint of the patient was decreased consciousness. These patients had different risk factors for stroke. According to the Siriraj score, NIHSS score, and neuroimaging findings, these patients had hemorrhagic strokes with different brain lesions. Two-thirds of the patients had uncontrolled hypertension and one patient was accompanied by uncontrolled diabetes mellitus. Conclusion: Overall, all patients were >45 years old and the risk factors of these patients were modified risk factors that is uncontrolled hypertension and diabetes mellitus over a long period resulting in ganglionic hemorrhage.
THE ASSOCIATION BETWEEN SERUM VITAMIN D LEVELS AND LIPID PROFILES AMONG PEOPLE WITH EPILEPSY Santoso Jaeri; Elisabeth Shanti Regita Putri; Caraka Adhika Rahardjo; Alivia Azka Fadhilah; Arinta Puspita Wati; Lusiana Batubara; Hardian Hardian
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 15, No 2 (2026): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v15i2.54625

Abstract

  Background and Purpose: Epilepsy, a neurological condition, is defined by the occurrence of unprovoked seizures on at least two occasions, with a minimum interval of 24 hours separating the initial and subsequent events. Individuals diagnosed with epilepsy frequently exhibit vitamin D deficiency, which influences various metabolic processes, including modifications to lipid profiles. Despite this, the precise relationship between serum vitamin D levels and lipid profiles continues to be a subject of ongoing investigation. This study aimed to examine the correlation between serum vitamin D concentration and lipid profiles. Methods: A cross-sectional study design was employed, encompassing 29 patients with epilepsy who were treated at the outpatient clinic of the Department of Neurology, Diponegoro National Hospital, Semarang. Participants were divided into two groups based on their serum vitamin D levels: the vitamin D deficiency group (n=9) and the vitamin D insufficiency group (n=20). Demographic and clinical information was gathered, vitamin D levels were measured using ELISA, and lipid profiles were assessed using spectrophotometry. A chi-square analysis was conducted to explore the relationship between serum vitamin D levels and lipid profiles in patients with epilepsy. Results: The average vitamin D concentration was 13.45 ± 5.74 ng/mL, with all participants showing deficient vitamin D. Examination of lipid profiles indicated mean values for total cholesterol at 183.76 ± 38.34 mg/dL, LDL cholesterol at 103.55 ± 34.92 mg/dL, HDL cholesterol at 48.72 ± 15.98 mg/dL, and triglycerides at 158.14 ± 104.48 mg/dL. Statistical analysis revealed that LDL levels were significantly elevated in the group with insufficient vitamin D (p = 0.029), while there were no significant differences in triglyceride, total cholesterol, or HDL levels. Statistical analysis revealed that LDL levels were significantly elevated in the group with insufficient vitamin D (p = 0.029), while there were no significant differences in triglyceride, total cholesterol, or HDL levels. Conclusion: There may be a link between low vitamin D levels and adverse LDL cholesterol levels; however, further research is required to confirm this.
Co-Authors Alivia Azka Fadhilah Amira Cinta Maharani Arinta Puspita Wati Caraka Adhika Rahardjo Diah Satyaningrum Elisabeth Shanti Regita Putri Gibran Chandra Syarif Hidayatullah Hardian Hardian Kayana Zahra Kallista Rambey Lusiana Batubara Maria Belladonna Rahmawati Sugianto Nadhira Faizah Putri Priambodo Nuzulur Rakhmah Nurulyana