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Aryani Aziz
Faculty of medicine, Universitas Sriwijaya, Jl. Dokter Muhammad Ali, Sekip Jaya, Kemuning, Palembang, Indonesia 30114
Medicine & Pharmacology

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Maternal and Perinatal Outcomes of Early and Late Onset Preeclampsia with Severe Features in Secondary Health Care Aryani Aziz; Uqbah Abdul Salam
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 14, No 1 (2025): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v14i1.46584

Abstract

Background: Preeclampsia is a condition characterized by new-onset hypertension during pregnancy, which can lead to various complications for both the mother and baby. It is categorized into early-onset preeclampsia (EO-PE) and late-onset preeclampsia (LO-PE) based on the timing of onset, each having distinct pathophysiologies and complications. Objective: This study aims to evaluate maternal and perinatal outcomes in patients with early and late-onset severe preeclampsia. Methods: An analytic observational study with a cross-sectional design was conducted at a secondary healthcare facility. The study included 554 women with severe preeclampsia who delivered at the facility, categorized into EO-PE and LO-PE groups. Maternal characteristics and outcomes, as well as perinatal outcomes, were analyzed. Results: Out of the total cases, 40 (7.22%) were EO-PE and 514 (92.78%) were LO-PE. Maternal outcomes such as HELLP syndrome, visual impairment, placental abruption, oliguria, ICU admission, and eclampsia were significantly higher in the EO-PE group. Additionally, perinatal outcomes including birth weight and APGAR scores were notably worse in the EO-PE group. Conclusion: Adverse maternal and perinatal outcomes were significantly more prevalent in early-onset preeclampsia compared to late-onset preeclampsia.
Co-Authors Uqbah Abdul Salam