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Climate Change and Public Health: Analysis of the Increasing Burden of Vector Borne Diseases in Tropical Countries Asnur Hi. Hukum
Journal of Public Health Indonesian Vol. 2 No. 4 (2025): November-JHH
Publisher : PT. Anagata Sembagi Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62872/7pqahj08

Abstract

Climate change is accelerating the transmission of vector borne diseases, particularly in tropical regions characterized by high temperatures, elevated humidity, and ecological conditions favorable for vector proliferation. This article examines the relationship between climate change and the rising burden of vector borne diseases such as dengue, malaria, chikungunya, and Zika through a Systematic Literature Review conducted in accordance with PRISMA guidelines. From 1,246 initially identified publications, 79 studies met inclusion criteria and were thematically synthesized. Findings indicate that increasing temperatures accelerate vector development and pathogen replication, rainfall variability expands breeding habitats, and high humidity prolongs vector survival. In tropical countries, rapid urbanization and infrastructural inequality further exacerbate disease risks, disproportionately affecting low income populations. The study highlights the need for climate informed early warning systems, innovative vector control methods, strengthened surveillance, and cross sector climate adaptation policies. These insights provide a scientific foundation for designing resilient public health strategies to address emerging vector borne disease threats in a warming climate
Formulasi Dan Uji Stabilitas Emulgel Herbal Kombinasi Minyak Cengkeh Dan Ekstrak Kulit Manggis Sebagai Kandidat Analgetik Topikal Asriaty Dinopawe; Marisa Anggia Ibrahim; Asnur Hi Hukum; Meisanti Ahdi
Jurnal Medika Malahayati Vol 10, No 1 (2026): Volume 10 Nomor 1
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jmm.v10i1.23674

Abstract

Minyak cengkeh (Syzygium aromaticum) dan ekstrak kulit manggis (Garcinia mangostana Linn.) memiliki potensi anti-inflamasi dan analgetik yang menjanjikan untuk sediaan topikal. Namun, studi yang mengevaluasi stabilitas fisik kombinasi minyak atsiri dan ekstrak kaya polifenol dalam satu sistem emulgel berbasis bahan alam masih sangat terbatas. Penelitian ini bertujuan untuk memformulasikan emulgel herbal, mengevaluasi stabilitas fisiknya melalui uji stabilitas dipercepat (cycling test), serta menguji keamanannya. Emulgel Formula B, yang mengandung Minyak Cengkeh 0,5% dan Ekstrak Kulit Manggis 1%, diformulasi menggunakan basis lidah buaya, gelatin, dan Tween 80. Sediaan dievaluasi melalui uji organoleptik, homogenitas, pH, viskositas, dan iritasi. Uji stabilitas dipercepat dilakukan melalui metode cycling test pada suhu 4°C dan 40°C selama 3 siklus (Siklus 0 hingga Siklus 3). Hasil menunjukkan sediaan berwarna coklat kemerahan, berbau khas cengkeh, homogenitas tetap stabil, dan memiliki nilai pH stabil pada 5,0 tanpa menimbulkan reaksi iritasi. Namun, stabilitas fisik sediaan terganggu secara signifikan, ditandai dengan perubahan tekstur dari kental menjadi cair setelah Siklus 2. Viskositas turun drastis secara statistik dari 1854,15 cP pada Siklus 0 menjadi 416,07 cP pada Siklus 3. Implikasi dari penelitian ini menunjukkan bahwa meskipun kombinasi bahan aktif tersebut aman dan biokompatibel dengan pH kulit, sistem basis gelatin-lidah buaya yang bersifat termolabil belum mampu mempertahankan integritas struktural terhadap fluktuasi suhu. Hal ini memberikan dasar penting bagi penelitian selanjutnya untuk mengoptimasi jenis dan konsentrasi gelling agent guna meningkatkan stabilitas termal sediaan analgetik herbal.
Climate Change and Public Health: Analysis of the Increasing Burden of Vector Borne Diseases in Tropical Countries Asnur Hi. Hukum
Journal of Public Health Indonesian Vol. 2 No. 4 (2025): November-JHH
Publisher : PT. Anagata Sembagi Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61536/jphi.v2i4.996

Abstract

Climate change is accelerating the transmission of vector borne diseases, particularly in tropical regions characterized by high temperatures, elevated humidity, and ecological conditions favorable for vector proliferation. This article examines the relationship between climate change and the rising burden of vector borne diseases such as dengue, malaria, chikungunya, and Zika through a Systematic Literature Review conducted in accordance with PRISMA guidelines. From 1,246 initially identified publications, 79 studies met inclusion criteria and were thematically synthesized. Findings indicate that increasing temperatures accelerate vector development and pathogen replication, rainfall variability expands breeding habitats, and high humidity prolongs vector survival. In tropical countries, rapid urbanization and infrastructural inequality further exacerbate disease risks, disproportionately affecting low income populations. The study highlights the need for climate informed early warning systems, innovative vector control methods, strengthened surveillance, and cross sector climate adaptation policies. These insights provide a scientific foundation for designing resilient public health strategies to address emerging vector borne disease threats in a warming climate