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Gambaran Tingkat Pengetahuan Tenaga Kefarmasian Tentang Penyerahan Obat Keras Tanpa Resep Dokter di Apotek Desa Waimital Zidna Di’inina Fakaubun; Azril Mahulauw; Dzulfikri Mewar
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 2 No. 2 (2024): April : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v2i2.135

Abstract

Introduction Hard drugs are drugs that have hard properties and if used carelessly or not according to the rules, can cause dangerous side effects and even poison the body, aggravate the disease, trigger the emergence of other diseases, to cause damage to body organs and death. Hard drugs are drugs that can only be obtained by prescription. Its characteristics are marked with a red round circle with a black border with the letter K in the middle that touches the border. This drug should only be sold in pharmacies and must be prescribed by a doctor at the time of buying it. While Mandatory Pharmacy Drugs (OWA) are some hard drugs that can be submitted without a doctor's prescription, but must be submitted by a Pharmacist at the pharmacy. This research method uses qualitative descriptive research design. What was used was total sampling with the measuring instrument used, namely a questionnaire with the number of samples being 15 respondents who became pharmaceutical personnel at the pharmacy. The results of the study showed that for the variable level of knowledge of pharmaceutical personnel with good categories amounted to 12 respondents with a percentage (80.0%) and enough 3 respondents with a percentage (20.0%), Kesimplant from the results of the level of knowledge of pharmaceutical personnel at pharmacies Waimital Village, Kairatu District, West Seram was good because pharmaceutical personnel knew information about hard drugs without a prescription and it was known that the pharmacist profession and the pharmacist assistant have the same level of understanding.
Formulasi Emulgel Ekstrak Daun Kopasanda (Chromolaena odorata L.) Menggunakan Carbopol 940 Sebagai Gelling Agent Nabila Aulia; Lukman La Basy; Ety Dusra; Dzulfikri Mewar; Maritje S.J Malisngorar
JURNAL KESEHATAN MALUKU HUSADA Vol 3, No 2 (2025): JULI-DESEMBER 2025
Publisher : STIKes Maluku Husada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/jkmh3205

Abstract

Daun kopasanda (Chromolaena odorata L.) mengandung flavonoid, saponin, dan tanin yang berperan sebagai antibakteri, antiinflamasi, dan antioksidan sehingga berpotensi mempercepat penyembuhan luka. Untuk meningkatkan efektivitas dan kenyamanan aplikasi topikal, ekstrak daun kopasanda diformulasikan dalam bentuk emulgel dengan Carbopol 940 sebagai gelling agent. Penelitian ini bertujuan memformulasikan ekstrak daun kopasanda menjadi emulgel serta mengetahui pengaruh variasi konsentrasi Carbopol 940 sebagai gelling agent terhadap stabilitas fisik sediaan emulgel ekstrak daun kopasanda (Chromolaena odorata L.). Metode penelitian bersifat eksperimental laboratorium. Ekstrak diperoleh melalui maserasi etanol 70%, kemudian diformulasikan menjadi emulgel dengan variasi konsentrasi Carbopol 940 (0,5%, 1%, 1,5%, dan 2%). Evaluasi mutu fisik meliputi uji organoleptik, pH, viskositas, daya sebar, dan daya lekat. Data dianalisis menggunakan uji Kruskal-Wallis. Hasil menunjukkan seluruh formula stabil secara organoleptik. Nilai pH rata-rata berada dalam rentang fisiologis kulit (F1 = 6; F2 = 5; F3 = 5; F4 = 5). Viskositas meningkat seiring kenaikan konsentrasi (F1 = 695 cps; F2 = 31.444 cps; F3 = 44.636,7 cps; F4 = 66.461,3 cps). Uji daya sebar rata-rata berkisar 6 cm (F1), 5,5 cm (F2), 5 cm (F3), hingga 4 cm (F4). Uji daya lekat menunjukkan peningkatan signifikan, dari 1,7 detik (F1), 2,6 detik (F2), 4,3 detik (F3) hingga 5,3 detik (F4). Analisis Kruskal-Wallis memperlihatkan perbedaan signifikan (p < 0,05) pada viskositas, daya sebar, pH dan daya lekat antar formula. Sehingga dapat disimpulkan bahwa ekstrak daun kopasanda dapat diformulasikan menjadi emulgel yang stabil, dengan Carbopol 940 konsentrasi 1,5% sebagai formula paling optimal.