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All Journal Jurnal Ners Indonesian Journal of Global Health Research
Molla Andriska Dewi
Universitas Sumatera Utara
Health Professions Medicine & Pharmacology Nursing

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Late Latent Syphilis in Pregnancy: A Case Report Molla Andriska Dewi; Kristina Nadeak
Jurnal Ners Vol. 9 No. 4 (2025): OKTOBER 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v9i4.50117

Abstract

Introduction Syphilis is a chronic sexually transmitted infection caused by Treponema pallidum, with latent stages posing particular risks in pregnancy due to vertical transmission and adverse fetal outcomes. Although treatable with penicillin, late latent syphilis often remains undiagnosed until routine antenatal screening. Case Presentation A 19-year-old woman, G2P1A0, at 21 weeks’ gestation, presented with a positive Venereal Disease Research Laboratory (VDRL) test during antenatal care. She denied history of genital ulcers, systemic symptoms, or multiple partners, but her husband had a history of untreated genital lesions and was seropositive for syphilis. Examination showed no mucocutaneous or systemic abnormalities. Laboratory evaluation confirmed late latent syphilis (VDRL 1:64; TPHA 1:5,120). The patient was treated with intramuscular benzathine penicillin G, 2.4 million units weekly for three weeks. Serial follow-up showed a progressive decline in VDRL titers (1:64 → 1:32 → 1:16 over six months). Pregnancy continued uneventfully. Conclusion Early detection and treatment of late latent syphilis in pregnancy are critical to prevent vertical transmission and adverse perinatal outcomes. Routine antenatal screening remains a cornerstone of maternal and child health programs.
Managing Tinea Cruris During Pregnancy: Therapeutic Dilemmas and Clinical Considerations Molla Andriska Dewi; Flora Marlita Lubis
Indonesian Journal of Global Health Research Vol. 7 No. 6 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i6.300

Abstract

Tinea cruris (dermatophytic infection of the groin) is a common superficial fungal infection. Increased levels of estrogen and progesterone during pregnancy can affect the immune system and skin homeostasis, creating a favorable environment for the growth of dermatophyte fungi. Its management during pregnancy poses clinical challenges, as the choice of antifungal therapy must balance maternal symptom relief with fetal safety. We report the case of a 21 years old pregnant woman in her third trimester who presented with pruritic, erythematous plaques in the inguinal region, clinically diagnosed as tinea cruris. Laboratory confirmation was achieved through potassium hydroxide (KOH) microscopy and fungal culture with sabaround dextrose agar. Considering gestational safety, topical terbinafine therapy was initiated, and systemic antifungals were avoided. Supportive measures, including hygiene optimization and avoidance of occlusive clothing, were reinforced. Symptomatic relief and lesion resolution were achieved within four weeks without maternal or fetal complications. The case highlights the therapeutic dilemma of managing tinea cruris in pregnancy, where systemic antifungals are often contraindicated. Topical terbinafine remain the mainstay of treatment, with satisfactory efficacy and safety profiles. Clinicians must carefully individualize therapy, prioritizing non-teratogenic options while ensuring effective infection control to prevent recurrence. Topical antifungal therapy is the mainstay of treatment for tinea cruris in pregnancy due to safety concerns with systemic agents. This case demonstrates that terbinafine cream is effective and well tolerated, with complete resolution and no maternal or fetal complications.
Histopathological Features of Basal Cell Carcinoma and Defect Reconstruction Using Rhomboid Flap: A Case Report Molla Andriska Dewi; T. Ibnu Alferraly; Remenda Siregar
Indonesian Journal of Global Health Research Vol. 7 No. 6 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i6.389

Abstract

Basal cell carcinoma (BCC) is the most prevalent type of nonmelanoma skin cancer, primarily associated with chronic ultraviolet exposure and typically affecting elderly individuals. This case report aims to describe the clinicopathological features and management of BCC in an 81-year-old woman who presented with a hyperpigmented nodule on the left mandibular region. A comprehensive approach was undertaken, including clinical assessment, dermoscopic evaluation, and histopathological examination. The lesion was surgically excised, and the resulting defect was reconstructed using a rhomboid flap. This procedure achieved complete tumor clearance and successful defect closure, with favorable aesthetic and functional outcomes and no postoperative complications. This case highlights the effectiveness of rhomboid flap reconstruction in restoring tissue intergrity following BCC excision, emphasizes the improtance of early diagnosis and histopathology confirmation, and highlights the role of surgical technique in optimizing patient prognosis. Furthermore, the findings contribute to the body of evidence supporting the rhomboid flap as a reliable option for facial reconstruction following oncologic surgery, enhancing postoperati ve recovery and quality of life for patients undergoing facial oncologic surgery.
Co-Authors Flora Marlita Lubis Kristina Nadeak Remenda Siregar T. Ibnu Alferraly