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Agrijanti
Health Polytechnic, Medical Laboratory Engineering Department, Mataram, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Materials Science & Nanotechnology Physics

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Investigating the Phytochemical Composition, GCMS Profile and Antimicrobial Effects of Nursehan Herbal Remedy for Sinusitis in Praya, Central Lombok Agrijanti; Lale Budi Kusumadewi; Ari Khusuma; Fathul Djannah; Siti Rahmatul Aini
Jurnal Penelitian Pendidikan IPA Vol 11 No 11 (2025): November
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i11.11125

Abstract

Recent studies emphasize the importance of medicinal plants in Indonesia's healthcare systems, where traditional remedies, including herbal formulations, are commonly used for treating ailments such as sinusitis. This research focuses on the Nursehan herbal remedy, a traditional treatment for sinusitis, used in Praya District, Central Lombok Regency. Nursehan is a combination of several plant materials, including Cinnamomum verum, Nauclea orientalis, and Nigella sativa, which are believed to alleviate sinus-related symptoms. However, scientific evidence supporting its efficacy remains limited. This study aims to validate the antimicrobial potential of Nursehan by analyzing its phytochemical profile and antibacterial activity. The Nursehan extract was prepared using a maceration method, and its chemical composition was assessed via GC-MS analysis, which identified key bioactive compounds such as hexadecanoic acid and 8-heptadecenoic acid, known for their antimicrobial and anti-inflammatory properties. Antimicrobial testing using the Kirby-Bauer method revealed significant antibacterial activity, particularly against Streptococcus pyogenes and Staphylococcus aureus. These findings provide scientific backing for the traditional use of Nursehan and highlight its potential as a therapeutic agent for sinusitis.
Co-Authors Ari Khusuma Fathul Djannah Lale Budi Kusumadewi Siti Rahmatul Aini