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ANALYSIS OF THE CLINICAL CHARACTERISTICS OF ORBITAL INFLAMMATION PATIENTS AT TERTIARY HOSPITAL IN EAST JAVA, INDONESIA Anggia dewi, Karina; Delfitri Lutfi; Kusuma Eko Purwantari; Indri Wahyuni
Majalah Biomorfologi 2026: MAJALAH BIOMORFOLOGI (IN PRESS)
Publisher : Universitas Airlangga, Surabaya, Indonesia

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Abstract

Background: Orbital inflammation is a benign inflammatory condition affecting the eye socket and can involve the orbital soft tissue, ocular muscles, and optic nerve. The diagnosis of orbital inflammation can be tricky due to the lack of standardized clinical criteria and the potential for overlap with other orbital diseases. Method: This retrospective, observational, and analytical study focused on patients diagnosed with orbital inflammation at The Outpatient Ophthalmology Oncology Clinic. Data from 68 samples that met the inclusion and exclusion criteria were classified and analyzed with descriptive statistics, and the Chi-square test and Odds Ratio (OR) was used to measure the likelihood of two clinical characteristics occurring together, indicating the strength of the relationship between paired symptoms that may commonly appear simultaneously in orbital inflammation. Result: Most patients were female (55.9%) and within the 18-75 age group (97.1%). Orbital inflammation predominantly presented unilaterally (89.7%). The study found that the most frequent clinical characteristics were proptosis, red eyes, decreased vision, and orbital pain. Among all assessed clinical characteristics, proptosis and red eye showed the most significant association, followed by proptosis and dry eye, red eye and eyelid edema, and proptosis and ptosis. Conclusion: Orbital inflammation presents with a wide range of clinical characteristics, reflecting the diverse inflammatory processes that may occur in the orbit. The study identified key clinical characteristics of orbital inflammation, including proptosis, red eyes, decreased vision, and orbital pain. Particularly between proptosis and red eye, followed by proptosis and dry eye, red eye and eyelid edema, and proptosis and ptosis. These clinical features, when found together, support clinicians in recognizing and establishing a diagnosis of orbital inflammation.