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Systematic Journal Review: Recent Developments in The Diagnosis and Therapeutic Management of Sinonasal Carcinoma Tolkha Amaruddin
Sehat Rakyat: Jurnal Kesehatan Masyarakat Vol. 5 No. 1 (2026): Februari 2026
Publisher : Yayasan Pendidikan Penelitian Pengabdian Algero

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54259/sehatrakyat.v5i1.6203

Abstract

Sinonasal carcinoma is a rare aggressive malignancy often detected at an advanced stage due to non-specific initial symptoms. This systematic review aims to summarize recent advances in diagnosis, including imaging technology and biomarkers, and to analyze current therapy management modalities to provide evidence-based recommendations. This study used a Systematic Journal Review (SLR) design following PRISMA guidelines to ensure transparency and accuracy, with a comprehensive literature search from databases such as PubMed and Scopus. Analyzed articles were limited to the last five years (2020-2025) and were narratively synthesized with data extraction covering diagnostic modalities, therapeutic strategies, and clinical outcomes. Trend and density visualization maps revealed a divided research focus: the clinical management cluster (sinonasal cancer, radiotherapy) as the foundation, and the diagnostic cluster (differential diagnosis, SMARCA4-deficient sinonasal ca) as the cutting-edge innovation. Analyzed studies confirmed the importance of genetic biomarkers such as SMARCA4 and HPV status for prognosis and therapy personalization. Overall, the current literature highlights a shift towards multimodal approaches and precision oncology that integrates molecular diagnosis to improve patient outcomes. This review confirms the integration of molecular diagnosis and personalized therapy management as the latest trend in sinonasal carcinoma treatment.
Systematic Journal Review: Management of Radiofrequency Ablation (RFA) for Thyroid Nodules Tolkha Amaruddin
Sehat Rakyat: Jurnal Kesehatan Masyarakat Vol. 5 No. 1 (2026): Februari 2026
Publisher : Yayasan Pendidikan Penelitian Pengabdian Algero

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54259/sehatrakyat.v5i1.6204

Abstract

Benign thyroid nodules are common and may cause compressive symptoms and cosmetic concerns, requiring effective treatment. Radiofrequency ablation (RFA) has emerged as a minimally invasive alternative to surgery; however, variations in technique and outcomes necessitate systematic evaluation. This study synthesizes recent evidence on the effectiveness and safety of RFA for benign thyroid nodules and identifies key technical factors influencing outcomes. A systematic review was conducted following PRISMA guidelines, analyzing studies published between 2020 and 2025 from major scientific databases. Ten eligible articles were included for qualitative synthesis. The results indicate that RFA consistently provides significant short- to mid-term nodule volume reduction, preserves thyroid function, and demonstrates a low complication rate. Most patients achieve optimal outcomes with a single ablation session, and long-term follow-up supports sustained efficacy. Recent international guidelines increasingly endorse RFA as a validated non-surgical treatment, including for large nodules previously managed surgically. The study recommends integrating RFA into national healthcare standards in Indonesia, supported by structured training and competency-based certification, to ensure quality and equitable access. Overall, RFA is confirmed as a safe, effective, and adaptable treatment modality with important implications for clinical practice and health policy.