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All Journal Jurnal Riset Rumpun Matematika dan Ilmu Pengetahuan Alam (JURRIMIPA)
Siti Khairunnur
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Mathematics

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Aktivitas Inhibisi Xantin Oksidase dan Antioksidan Ekstrak Etanol Daun, Batang, serta Kombinasinya dari Serai (Cymbopogon citratus) secara In Vitro Besse Illang Sari; Siti Khairunnur; Andi Yanti Puspita Sari; Muhammad Mulyadi Nahrun
JURNAL RISET RUMPUN MATEMATIKA DAN ILMU PENGETAHUAN ALAM Vol. 4 No. 3 (2025): Desember : JURRIMIPA: Jurnal Riset Rumpun Matematika dan Ilmu Pengetahuan Alam
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrimipa.v4i3.8357

Abstract

Lemongrass (Cymbopogon citratus) is a plant known to contain various bioactive compounds with potential antioxidant properties as well as xanthine oxidase (XO) inhibitory activity. This study aimed to evaluate the phytochemical content, antioxidant activity, and XO inhibitory potential of ethanol extracts from the leaves, stems, and their combination. Phytochemical screening revealed that all extracts contained alkaloids, flavonoids, and terpenoids, while phenolic compounds were detected only in the leaf extract and the combined leaf–stem extract. Antioxidant activity assays demonstrated that all extracts exhibited very strong antioxidant activity, with IC₅₀ values below 50 ppm, indicating a significant potential to scavenge free radicals. In the XO inhibition assay at a concentration of 200 ppm, the ethanol extract of lemongrass stems showed the highest inhibitory activity at 81.37%, followed by the leaf extract at 48.08% and the combined leaf–stem extract at 33.65%. Overall, these findings suggest that the ethanol extract of lemongrass stems is the most promising natural source of antioxidants and has the greatest ability to inhibit xanthine oxidase activity, indicating its potential development as a functional ingredient for health applications.
Adsorpsi Selektif Ion Cd2+ Menggunakan Silika Mesopori MCM-48-NH2 Andi Yanti Puspita Sari; Muhammad Mulyadi Nahrun; Besse Illang Sari; Siti Khairunnur
JURNAL RISET RUMPUN MATEMATIKA DAN ILMU PENGETAHUAN ALAM Vol. 4 No. 3 (2025): Desember : JURRIMIPA: Jurnal Riset Rumpun Matematika dan Ilmu Pengetahuan Alam
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrimipa.v4i3.8358

Abstract

The danger of cadmium contamination in water sources remains a crucial environmental issue due to its persistent nature and high toxicity level, which poses serious risks to human health and ecosystems. Cadmium is a non-biodegradable heavy metal that can accumulate in living organisms over time. The presence of these toxic Cd²⁺ ions is known to trigger damage to vital organs such as the liver and kidneys; therefore, reducing their concentration in aquatic environments is of paramount importance for environmental protection and public health safety. Among various treatment methods, adsorption is considered one of the most effective and economical techniques for removing heavy metal ions from contaminated water. In this study, the capability of mesoporous silica MCM-48-NH₂ as an adsorbent for Cd²⁺ ions was systematically evaluated. The adsorption performance was examined by investigating several important parameters, including contact time, solution acidity level (pH), and initial Cd²⁺ concentration. Furthermore, the adsorption mechanism and interaction between Cd²⁺ ions and the adsorbent surface were analyzed using Langmuir and Freundlich isotherm models. The results demonstrate that the adsorption process of Cd²⁺ ions onto MCM-48-NH₂ tends to follow the Langmuir isotherm model, indicating monolayer adsorption behavior, with a maximum adsorption capacity of 0.66 mmol g⁻¹.
Co-Authors Andi Yanti Puspita Sari Besse Illang Sari Muhammad Mulyadi Nahrun