Article Per Year (5 Year)
p-Index From 2021 - 2026
0.444
P-Index
This Author published in this journals
All Journal Edumatsains Jurnal Pembelajaran dan Biologi Nukleus
Sanna Kamisna Royani Purba
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Education Environmental Science Immunology & microbiology Languange, Linguistic, Communication & Media Mathematics Physics

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
The Impact Of Pesticide Residue Accumulation On The Reduction Of Blood Cholinesterase Enzyme Levels In Dragon Fruit Farmers In Karo Land Radina Yuni Mahesa Ginting; Sanna Kamisna Royani Purba; Mira Hastari Ginting; Atri Gustiana Gultom
EduMatSains : Jurnal Pendidikan, Matematika dan Sains Vol 10 No 3 (2026): January
Publisher : Fakultas Keguruan dan Ilmu Pendidikan, Universitas Kristen Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33541/edumatsains.v10i3.7644

Abstract

Pesticide use has a negative impact on dragon fruit farmers. According to the World Health Organization (WHO), an estimated 1-5 million people experience pesticide poisoning annually, with a mortality rate of 220,000 deaths. Individuals experiencing pesticide poisoning will have low cholinesterase levels. This decreased enzyme activity can lead to nervous system disorders, poisoning, and even death. This study aimed to determine the effect of pesticide accumulation on the decline in cholinesterase enzyme levels among dragon fruit farmers in Berastepu Village, Tanah Karo. Blood samples were examined at the MCI Indonesia Clinical Laboratory. A descriptive approach was used in this study, with blood samples collected from dragon fruit farmers. The results showed that 11 farmers had normal cholinesterase levels, while 4 farmers had abnormal levels. The average values ​​were normal (170.0-420 U/L) and abnormal (<170.0-420 U/L). The conclusion of the study with 15 samples was the cholinesterase levels in farmers who were exposed to pesticides 1-3 times a week with an age range of 31-40 years and 41-50 years.
Formulation Cream of Ethanol Patikan Kebo Weeds (Euphorbia hirta L.) Extract As An In Vitro Anti-Acne Lydia Br Barus; Sanna Kamisna Royani Purba; Sesilia Sri Susandri Br. Gultom; Helen Anjelina Simanjuntak; Hermawan Purba; Nurbaiti Br. Singarimbun; Defacto Firmawati Zega
JURNAL PEMBELAJARAN DAN BIOLOGI NUKLEUS Vol 11, No 2: Jurnal Pembelajaran Dan Biologi Nukleus June 2025
Publisher : Universitas Labuhanbatu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36987/jpbn.v11i2.6698

Abstract

Background: Acne is a skin inflammation that is prevalent in 80-100% of the population, particularly during adolescence.  The Patikan Kebo (Euphorbia hirta L.) weed plant is employed in a cream formulation to treat acne. Therefore, this study aims to determine the formula of the Patikan Kebo (E. hirta L.) weed cream preparation that is as effective as an in vitro anti-acne. Methodology: the research method was carried out experimentally with the stages of sample preparation, phytochemical screening, extraction, formulation, evaluation, and antibacterial activity test that caused acne using the well diffusion method. Findings: The results showed the Patikan Kebo (E. hirta L.) weed has secondary metabolites consisting of alkaloids, flavonoids, saponins, tannins, and steroids/triterpenoids. The evaluation of the cream preparation of each formula has met cosmetic standards. The diameter of the F4 inhibition zone has antibacterial activity against acne-causing Propionibacterium acnes (12.03 ± 0.81 mm), Staphylococcus epidermidis (11.48 ± 1.10 mm), S. aureus (12.07 ± 0.06 mm), and the F5 inhibition zone P. acnes (13.53 ± 0.15 mm), S. epidermidis (12.54 ± 0.75 mm), and S. aureus (13.03 ± 0.61 mm). Formulas F4 and F5 are more effective as anti-acne with a strong inhibition zone diameter. Contribution: These findings indicate that formulas F4 and F5 can be further developed as alternative natural active ingredients in cosmetic or pharmaceutical products for acne therapy, thus contributing to the development of safer, more economical, and more sustainable local herbal medicine
Co-Authors Atri Gustiana Gultom Defacto Firmawati Zega Helen Anjelina Simanjuntak Hermawan Purba Lydia Br Barus Mira Hastari Ginting Nurbaiti Br. Singarimbun Radina Yuni Mahesa Ginting Sesilia Sri Susandri Br. Gultom