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Perbandingan Efektivitas Diazepam dan Magnesium Sulfat dalam Penanganan Kejang pada Tetanus: Tinjauan Literatur Iwan Setiawan Adji; Lina Nur Fatimah; Dhia Laila Nadzifa; Witrishya Anggrahini; Noval Gentha Mahensa
SEHATMAS: Jurnal Ilmiah Kesehatan Masyarakat Vol. 4 No. 4 (2025): Oktober 2025
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/sehatmas.v4i4.6414

Abstract

Seizures are a serious complication of tetanus, contributing to high morbidity and mortality rates. Various therapeutic approaches have been employed to manage seizures, including diazepam and magnesium sulfate. This literature review aims to compare the effectiveness of these two agents in reducing both the frequency and severity of seizures in tetanus patients. A systematic search was conducted using scientific publications from PubMed, Google Scholar, and ScienceDirect over the past ten years. The review indicates that magnesium sulfate shows potential as an effective and relatively safe alternative to diazepam in certain clinical settings. However, variations in study design and limited available data highlight the need for further clinical trials to strengthen existing evidence. This review is expected to serve as a reference for clinicians in selecting optimal anticonvulsant therapy for tetanus cases. Furthermore, the study emphasizes the importance of understanding the pharmacological mechanisms, clinical indications, and monitoring of adverse effects to ensure both safety and efficacy of the therapy. Overall, this literature review contributes to the development of evidence-based clinical guidelines for managing seizures in tetanus patients.
THE INFLUENCE OF SERVICE QUALITY DIMENSIONS ON PATIENT LOYALTY WITH SATISFACTION AS A MEDIATING VARIABLE AT PKU MUHAMMADIYAH WONOGIRI HOSPITAL Khusnul Khotimah Ariyani; Iwan Setiawan Adji; Soepatini
Multidiciplinary Output Research For Actual and International Issue (MORFAI) Vol. 6 No. 3 (2026): Multidiciplinary Output Research For Actual and International Issue
Publisher : RADJA PUBLIKA

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

This study aims to analyze the influence of service quality dimensions, including tangible, reliability, responsiveness, assurance, and empathy, on patient loyalty, with patient satisfaction as a mediating variable at PKU Muhammadiyah Wonogiri Hospital. This study employed a quantitative, survey-based approach. The sample consisted of 200 outpatients selected using purposive sampling. Data were collected using a Likert-scale questionnaire and analyzed using Partial Least Squares–Structural Equation Modeling (PLS-SEM) with SmartPLS. The results showed that reliability, assurance, and empathy had a positive and significant effect on patient satisfaction, while tangibles and responsiveness did not significantly influence satisfaction. Patient satisfaction had a positive and significant effect on patient loyalty. Furthermore, tangibles, assurance, and empathy had a direct significant effect on patient loyalty, while reliability and responsiveness did not show significant direct effects. The mediation analysis revealed that patient satisfaction significantly mediated the relationship between empathy and patient loyalty, while the mediating effect of satisfaction on the relationship between reliability and loyalty was weak or marginal. In contrast, satisfaction did not mediate the relationships between tangibles, responsiveness, or assurance and patient loyalty. These findings indicate that emotional and interpersonal aspects of healthcare services, particularly empathy, play a central role in enhancing patient satisfaction and loyalty. Therefore, hospitals are encouraged to strengthen healthcare worker–patient interactions to improve long-term patient loyalty.