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All Journal Jurnal Penelitian Kesehatan Suara Forikes
Huda, Mega Hasanul
Faculty of Nursing, Universitas Indonesia, Depok
Health Professions Medicine & Pharmacology Nursing Public Health

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Diagnostic Accuracy of Neonatal Sepsis Scoring Systems in Preterm Infants Rudy, Rudy; Huda, Mega Hasanul; Chodidjah, Siti
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 17, No 1 (2026): January 2026
Publisher : FORIKES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf170120

Abstract

Neonatal sepsis remains a major cause of morbidity and mortality among preterm infants, particularly in low- and middle-income countries. Early identification through clinical scoring systems, such as the Singh Score, Rosenberg Score, and Bekhof Score, may improve diagnostic accuracy and support timely management. This study aimed to systematically evaluate the diagnostic performance of these three clinical scoring instruments in detecting neonatal sepsis. A systematic search was conducted across seven electronic databases from inception to August 2025. Studies assessing the diagnostic accuracy of the selected scoring systems were included, critically appraised, and analyzed. Data on sensitivity, specificity, and other diagnostic accuracy measures were extracted and synthesized. Five eligible studies were identified, most of which were conducted in low- and middle-income countries, with sample sizes ranging from 80 to 658 neonates. The pooled sensitivity of the three instruments ranged from 0.56 to 0.76, with the Singh Score demonstrating the highest sensitivity (76%), followed by the Bekhof (63%) and Rosenberg (56%) scores. The pooled specificity ranged from 0.33 to 0.69, indicating low to moderate ability to exclude non-sepsis cases. Overall, these instruments demonstrate moderate sensitivity but limited specificity and are more suitable for ruling out sepsis rather than definitively confirming the diagnosis. Their use should be integrated with comprehensive clinical assessment and additional laboratory investigations. These scoring systems may aid in risk stratification and help reduce unnecessary treatment by identifying neonates at low risk of sepsis.Keywords: neonatal sepsis; preterm infants; clinical scoring system; diagnostic accuracy
Sensory Stimulation Improves Neurobehavioral Development in Preterm Infants Alimuddin, Rahmatika; Allendekania, Allendekania; Yustina, Reni; Huda, Mega Hasanul
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 17, No 4 (2026): April 2026
Publisher : FORIKES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf170407

Abstract

Prematurity disrupts critical intrauterine sensory experiences and increases the risk of long‑term neurobehavioral developmental impairments in infants, particularly those receiving care in the Neonatal Intensive Care Unit (NICU). Sensory stimulation interventions offer a non‑pharmacological approach to support central nervous system maturation in preterm infants. This systematic review aimed to evaluate the effects of sensory stimulation on neurobehavioral development in preterm infants. Literature searches were conducted using the Population–Intervention–Comparison–Outcome (PICO) framework across PubMed, ProQuest, and ScienceDirect, focusing on randomized controlled trials published between 2015 and 2025. The review followed the Preferred Reporting Items for Systematic Reviews and Meta‑Analyses (PRISMA) guidelines, and methodological quality was assessed using the Joanna Briggs Institute (JBI) Critical Appraisal Tools. Seven studies met the inclusion criteria. All reported significant improvements in neurobehavioral outcomes measured using the Neonatal Neurobehavioral Examination Scale (NNES), Neonatal Intensive Care Unit Network Neurobehavioral Scale (NNNS), Munich Neuromotor Development Examination (MNNE), Neonatal Behavioral Assessment Scale (NBAS), Dubowitz Neurological Examination, Alberta Infant Behavioral Scale (ABSS), and Infant Behavior Questionnaire‑Revised (IBQ‑R). Additional benefits included improved suck coordination, increased weight gain, enhanced physiological stability, and reduced length of hospital stay. In conclusion, sensory stimulation, particularly multisensory approaches effectively enhances neurobehavioral development in preterm infants and is recommended for integration into NICU care and early family‑centered intervention programs.Keywords: preterm infants; Neonatal Intensive Care Unit; neurobehavioral development; sensory stimulation
Co-Authors Alimuddin, Rahmatika Allendekania, Allendekania Chodidjah, Siti Rudy, Rudy Yustina, Reni