Article Per Year (5 Year)
p-Index From 2021 - 2026
0.444
P-Index
This Author published in this journals
All Journal Biomedical Journal of Indonesia Journal of General Procedural Dermatology and Venereology Indonesia
Novriani, Rina
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Comparative Susceptibility of Staphylococcus aureus and S. pyogenes to Musa paradisiaca Linn Leaf Extract and Fusidic Acid in Impetigo Patients Inda Astri Aryani; Winny Astria, Maretha; Novriani, Rina; Amelinda, Aulia Rosa
Biomedical Journal of Indonesia Vol. 12 No. 1 (2026): Vol 12, No 1, 2026
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v12i1.298

Abstract

Introduction. An estimated 12% of the world’s population is at risk of experiencing impetigo. The prevalence of impetigo in developing countries ranges from 111 to 140 million cases. Impetigo often occurs in children aged 2-5 years. One way to overcome this condition involves using natural products or phytochemicals that are effective, safe, and economical. One of the Indonesian plants that can be used as an alternative medicine with antibacterial effects is the kepok banana leaves (Musa paradisiaca Linn). This study aimed to assess the susceptibility of S. aureus and S. pyogenes to the antimicrobial potential of the extract of M. paradisiaca leaf extract and fusidic acid using isolates from impetigo patients. Methods. This in vitro experimental study used a post-test-only control-group design. Bacterial isolates were obtained from impetigo patients and tested using the disk diffusion method following CLSI standards. Group comparisons were conducted using the Kruskal–Wallis test followed by Mann–Whitney U tests. A p-value < 0.05 was considered statistically significant. Results. Bivariate analysis showed a significant difference in the susceptibility of S. aureus between fusidic acid and M. paradisiaca extract (p < 0.05), where fusidic acid demonstrated larger inhibition zones. Similarly, a significant difference was observed for S. pyogenes (p < 0.05). However, there was no significant difference between the 50% and 100% extract concentrations. Conclusion. M. paradisiaca leaf extract exhibits antibacterial activity against S. aureus and S. pyogenes, but is significantly less effective than standard fusidic acid treatment in vitro.
Association between vitamin D and cholesterol in post-acne hypertrophic scars and keloids: A cross-sectional study Kurniawati, Yuli; Yahya, Yulia Farida; Diba, Sarah; Novriani, Rina; Yusuf, Hasbiallah; Martgaredta, Ekta
Journal of General - Procedural Dermatology and Venereology Indonesia Vol. 9, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Post-acne hypertrophic scars and keloids result from abnormal wound healing within the pilosebaceous unit. Ruptured microcomedones create wounds that can lead to prolonged inflammation, increased collagen synthesis, and fibrinolysis inhibition, resulting in elevated scar tissue in acne lesions. Vitamin D deficiency can lead to prolonged inflammation and damage to dermal collagen. High total cholesterol levels can lead to excessive sebum production, exacerbating inflammation and fibrosis. This study aimed to determine the association between serum vitamin D and total cholesterol levels with scar severity in patients with post-acne hypertrophic scars and keloids. Methods: This analytical cross-sectional study was conducted at Dr. Mohammad Hoesin General Hospital, Palembang, South Sumatera, Indonesia, among patients who met the inclusion and exclusion criteria. Scar severity was assessed using the Vancouver Scar Scale (VSS). Blood samples were collected for examination of serum vitamin D and total cholesterol. The data were analyzed statistically. Results: Chi-square test of serum vitamin D with VSS scores showed a significant association (p-value = 0.007), while total cholesterol with VSS showed no association (p-value = 1.000). Odd-ratio (OR) for serum vitamin D and VSS was 60, concluding that vitamin D deficiency increased the risk of high VSS by 60-fold in study patients. Conclusion: There was a significant association between serum vitamin D levels and VSS score, while there was no association between total cholesterol and VSS score. Deficiency of serum vitamin D is associated with a higher risk of developing a higher VSS score in patients with post-acne hypertrophic scars and keloids.
Co-Authors Amelinda, Aulia Rosa Diba, Sarah Inda Astri Aryani Martgaredta, Ekta Winny Astria, Maretha Yuli Kurniawati, Yuli Yulia Farida Yahya Yusuf, Hasbiallah