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p-Index From 2021 - 2026
0.408
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All Journal International Journal of Health, Engineering and Technology
Batara Imanuel Sirait
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Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Dentistry Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Mechanical Engineering Medicine & Pharmacology Nursing Public Health Veterinary

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Factors Associated With Pregnancy Outcomes After Intrauterine Insemination Batara Imanuel Sirait; Frisca Angreni; Indira Naomi Hutahaean
International Journal of Health Engineering and Technology Vol. 4 No. 6 (2026): IJHET MARCH 2026
Publisher : CV. AFDIFAL MAJU BERKAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55227/ijhet.v4i6.682

Abstract

Infertility is a reproductive disorder defined as the inability to achieve a clinical pregnancy after 12 months or more of regular unprotected intercourse. It may be caused by female and/or male factors. Intrauterine insemination (IUI) is a form of assisted reproduction commonly used to treat subfertility. In Indonesia, infertility affects an estimated 10–15% of couples, equivalent to 4–6 million out of 29.8 million couples of reproductive age. This study aimed to evaluate factors associated with pregnancy success following IUI at Morula IVF Clinic, Jakarta, during January - December 2023. An analytic descriptive design was applied, and associations were tested using the Chi-square method. A total of 199 patients were included, with an overall IUI pregnancy success rate of 8.5%. Successful pregnancies were most frequently observed among wives aged 25 - 35 years, those with a body mass index of 18.5–24.9 kg/m², and cycles with pre-wash semen volume of 2 - 5 mL, sperm concentration >16 million, and sperm motility >30%. Chi-square analysis demonstrated that only sperm motility was significantly associated with IUI success (p=0.029), while wife’s age, body mass index, pre-wash semen volume, and sperm concentration showed no significant association.
D-Dimer In Pregnancy Danny Ernest Jonas Luhulima; Batara Imanuel Sirait
International Journal of Health Engineering and Technology Vol. 4 No. 6 (2026): IJHET MARCH 2026
Publisher : CV. AFDIFAL MAJU BERKAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55227/ijhet.v4i6.696

Abstract

D-dimer is a fibrin degradation product that serves as a vital biomarker in the fibrinolytic system. This review aims to examine the role and mechanism of D-dimer during pregnancy and its measurement methods. The method used is a literature review of clinical studies and references related to hemostasis in pregnancy. Results show that pregnancy physiologically increases coagulation activity as a natural mechanism to prevent hemorrhage during delivery. Increased D-dimer levels are found in 27% of first-trimester pregnancies, 87% in the second trimester, and 100% in the third trimester. Pathological conditions such as preeclampsia, eclampsia, and venous thromboembolism (VTE) risks are closely linked to significant surges in D-dimer levels. While ELISA remains the gold standard for D-dimer testing, immunoturbidimetric and immunofiltration methods are more commonly used due to their speed and efficiency. In conclusion, although D-dimer levels naturally rise during pregnancy, monitoring this parameter is crucial for predicting medical emergencies like disseminated intravascular coagulation (DIC) to reduce maternal mortality rates.
Co-Authors Danny Ernest Jonas Luhulima Frisca Angreni Indira Naomi Hutahaean