Article Per Year (5 Year)
p-Index From 2021 - 2026
0.408
P-Index
This Author published in this journals
All Journal ILMU KELAUTAN: Indonesian Journal of Marine Sciences Journal of Marine Research
Sri Sedjati
Department of Marine Science, Faculty of Fisheries and Marine Science, Universitas Diponegoro
Earth & Planetary Sciences

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Analysis of Heavy Metal Content in Odaiba Waters, Japan Using Inductively Coupled Plasma Mass Spectrometry (ICP-MS) Hasya Ainun Nashih; Takato Negishi; Kuo Hong Wong; Asami Mashio; Hiroshi Hasegawa; Ali Ridlo; Sri Sedjati
Journal of Marine Research Vol 15, No 1 (2026): Journal of Marine Research
Publisher : Departemen Ilmu Kelautan, Fakultas PerikanJurusan Ilmu Kelautan, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jmr.v15i1.53234

Abstract

This study aims to determine the content of dissolved heavy metals (Mn, Co, Ni, Cu, Zn, Cd, Pb) using Inductively Coupled Plasma Mass Spectrometry (ICP-MS). This method was chosen because it has high sensitivity and the ability to detect elements in ultra-low concentrations accurately. Water samples were collected on July 13, 2024, and analyzed using selective resin and UV irradiation for the separation of metals. The results showed that primary metals (Zn, Mn, Ni, Cu) exceeded the CASS-6 reference limits, with Zn having the highest concentration (88.69 ± 1.92 nM). In contrast, minor metals (Cd, Pb, Co) were below the reference values, reflecting a stable distribution of heavy metals. The increase in significant metal concentrations is thought to be related to the timing of sampling in the summer, which coincides with the rainy season, potentially increasing runoff carrying heavy metals from the city center and industry to the waters of Odaiba. The detection results of minor metals in this study indicate that ICP-MS is effective for measuring heavy metal content at very low quantities. Environmental parameters, such as pH, temperature, and salinity, are also believed to influence the solubility and mobility of metals.
Marine-Derived Matairesinol: A Potential Antimicrobial Agent Against Klebsiella pneumoniae from Sponge-Associated Trichoderma longibrachiatum Sri Sedjati; Ambariyanto Ambariyanto; Agus Trianto; Gunawan W. Santosa; Muhammad S. Bahry; Ayunda Ainun Nisa
ILMU KELAUTAN: Indonesian Journal of Marine Sciences Vol 31, No 2 (2026): Ilmu Kelautan
Publisher : Marine Science Department Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/ik.ijms.31.2.159-168

Abstract

The fungus Trichoderma sp., which is associated with marine sponges, produces various antibacterial compounds that can be used as lead compounds for new antibiotics. The ethyl acetate extract of the sponge-associated fungus Trichoderma longibrachiatum contains an active compound that inhibits the growth of Klebsiella pneumoniae. This study aimed to identify the sponge host and determine the active compound produced by this fungus with anti-K. pneumoniae activity. This study began with a sample of fungal cultures and the identification of the host sponge. The extract samples were obtained using a partition method between methanol and ethyl acetate. Determination of antibacterial compounds in ethyl acetate extracts using disc diffusion and bioautography. Active compounds were identified using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) and Nuclear Magnetic Resonance Spectroscopy (NMR). The results showed that the host sponge of T. longibrachiatum is Axinella sp. The ethyl acetate extract exhibited antibacterial activity against K. pneumoniae, with inhibition zones of 10.12 and 14.45 mm at doses of 250 and 500 μg discs-1,respectively. The bioautography test revealed that the active fraction had a retardation factor (Rf) of 0.14. The active compound was isolated and anti-K. pneumoniae was identified as matairesinol (C20H22O6), also known as (3R,4R)-3,4-bis[ (4-hydroxy-3-methoxyphenyl) methyl]oxolan-2-one). Matairesinol is a polyphenol from the lignan group with a gamma (γ)-lactone ring. The isolation of matairesinol as an active antibacterial compound against K. pneumoniae provides valuable insights into the potential of marine-derived fungi as a source of novel antimicrobial agents.
Co-Authors Agus Trianto Ali Ridlo Ambariyanto Ambariyanto Asami Mashio Ayunda Ainun Nisa Gunawan W. Santosa Hasya Ainun Nashih Hiroshi Hasegawa Kuo Hong Wong Muhammad S. Bahry Takato Negishi