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p-Index From 2021 - 2026
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All Journal Jurnal Respirologi Indonesia Malang Respiratory Journal
Fanny Fachrucha
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Other

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Interstitial Lung Disease Related to Dematomyositis: Rare Case Dian Megawati; Fanny Fachrucha
Malang Respiratory Journal Vol. 8 No. 1 (2026): Volume 8 No 1, March 2026 Edition
Publisher : Universitaas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mrj.2026.008.01.05

Abstract

Background: Dermatomyositis is a rare disease caused by inflammation of the muscles and connective tissues. One of the most common complications is interstitial lung disease (ILD) caused by a humoral immune response. Case: The case presented is a 48-year-old woman with classic symptoms of DM accompanied by respiratory symptoms and low lung fuctiond who was objectively proven to have ILD as a complication. Multidisciplinary collaboration was carried out to treat the patient. Conclusion: ILD is one of the complication and predictors of poor prognosis in DM patients. Comprehensive management and regular monitoring are needed to inhibit disease progression. Keywords: dermatomyositis, complication, ILD
A Compounding Challenge: An Evidence-Based Case Report on the Link Between Obesity and Asthma Exacerbations in Pregnancy Muhammad Bimo Ramadhan; Halidza Nursasqia Pasyah; Aurora Serena Ueda; Rafi Akbar Putranto; Fanny Fachrucha
Jurnal Respirologi Indonesia Vol 46 No 2 (2026)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/eqb78x22

Abstract

Background: Asthma exacerbations in pregnancy have been found to increase risk of adverse perinatal outcomes. Obesity during pregnancy, a condition of rising prevalence, is hypothesized to worsen asthma control through inflammatory mechanisms. However, the scientific evidence on the association between the two variables remains contradictory. This Evidence-Based Case Report aims to determine the association between early-pregnancy obesity and asthma exacerbation during pregnancy by synthesizing findings from various related studies. Methods: A literature search was conducted using relevant keywords from utilized databases: PubMed, ScienceDirect, Cochrane, and ClinicalTrials.gov. The Oxford Centre for Evidence-Based Medicine (CEBM) framework was used to appraise the literature that met the inclusion and exclusion criteria. Results: This review identified five studies, comprising one systematic review and meta-analysis and four cohort studies. These studies were appraised as valid, important, and applicable. Four of the five studies reported significant increased risk of asthma exacerbation in pregnant women with early-pregnancy obesity. The study by Stevens et al. (2022) reported a decreased risk of exacerbation in pregnant women with obesity compared to the control group, attributing this to differences in perception thresholds between the groups and the possibility of study bias. Conclusion: Pregnant women with obesity in early pregnancy have a higher risk of experiencing asthma exacerbations during pregnancy compared to non-obese groups. Therefore, this condition requires enhanced monitoring and asthma management to prevent maternal and perinatal complications.
Co-Authors Aurora Serena Ueda Dian Megawati Halidza Nursasqia Pasyah Muhammad Bimo Ramadhan Rafi Akbar Putranto