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All Journal African Journal of Sciences and Traditional Medicine
Benjamin O. Gabriel
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Chemistry Health Professions Immunology & microbiology Nursing Public Health

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Perception of Herbal Medicine in the Management of Ocular Hypertension: A Case Study of Egor Local Government Area, Edo State Stella E. Odjimogho; Faith Osemudiamen Ogbeide; Sunny E. Odjimogho; Benjamin O. Gabriel
African Journal of Sciences and Traditional Medicine Vol 2 No 1 (2025): African Journal of Sciences and Traditional Medicine
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajstm.v2i1.4589

Abstract

Traditional medicine is “the knowledge, skills and practices based on the theories, beliefs and experiences indigenous to different cultures. This study was to determine the perception of preference for traditional medicine to modern medicine in the management of ocular problems amongst adults aged between 18-80 years, in Egor local government area, Benin city. A cross- sectional study was conducted on adults residing in Egor local government area, Benin city with the use of an interview-based questionnaire. The results of this study showed that 39 representing 16.9% of the respondents in the study population used traditional medicine while 180 representing 77.9% without the use of traditional medicine. However, there was no statistically difference between the socio-demographic variables and the use of traditional eye medicines (P>0.05). In conclusion, this study will help clinicians to gain knowledge on the reasons for preference of traditional medicine to orthodox medicine in the treatment of eye problems. It would enable Eye care practitioners increase advocacy on the possible consequences of their choices in order to help the people make informed decisions. It is therefore recommended there should be public enlightenment on the possibility of adverse effects in traditional medicine for the management of ocular problems.
Anti-intra Ocular Pressure of Stachytarpheta jamaicensis Leaf Aqueous Extract on Prednisolone-Induced intra Ocular Pressure in Rabbits Stella E. Odjimogho; MacDonald Idu; Sunny E. Odjimogho; Benjamin O. Gabriel
African Journal of Sciences and Traditional Medicine Vol 2 No 1 (2025): African Journal of Sciences and Traditional Medicine
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajstm.v2i1.4590

Abstract

Intraocular pressure is generated by the dynamics of secretion and outflow of aqueous humour, a transparent colorless fluid (secretion) that fills the complex space in the front part of the eye. This study is aimed at investigating the effect of Stachytarpheta jamaicensi leaf aqueous extract on induced intraocular pressure (IOP) in rabbits to validate its ocular potential. The experiment involved twenty five (25) healthy adult rabbits (n=5), divided into negative positive and positive control (0.5% timolol), and the treatment groups (SJ) at graded concentrations (0.00351, 0.00702 and 0.0143 mg/ml).The baseline IOP value of all rabbits were measured with Perkins hand-held applanation tonometer before the commencement of the study. Thereafter, the IOP of the experimental and treatment groups were induced with daily instillation of 1% prednisolone suspension for one week until IOP reading was 5 mm. Hg above the baseline level. The treatment groups were administered with varying concentrations of the aqueous extract of Stachytarpheta jamaicensis. The IOP was also measured at intervals before each application of aqueous extract until the IOP returned to baseline level. The result showed the distribution of the mean IOP before, and after instillation with 1% Prednisolone suspension and the treatment with varying concentrations of S. jamaicensis extract. The observed mean IOP before and after the treatment with prednisolone was 8.77±0.5 mmHg, and 14.2±0.51 mmHg respectively. After oral application of S. jamaicensis extract had a significant mean IOP decrease across the days when compared with the controls. The decrease in mean IOP was observed with a significant increase at higher concentrations of the extract, hence the plant caused a reduction in IOP level. Inconclusion, the plants have been implicated in reducing intraocular pressure in rabbits, thus may be helpful in the management of intraocular pressure (IOP), thereby, required further study to validate the efficacy of the extract.
Co-Authors Faith Osemudiamen Ogbeide MacDonald Idu Stella E. Odjimogho Sunny E. Odjimogho