Article Per Year (5 Year)
p-Index From 2021 - 2026
0.947
P-Index
This Author published in this journals
All Journal Pharmacology and Clinical Pharmacy Research Prima Abdika: Jurnal Pengabdian Masyarakat Jurnal Redoks : Jurnal Pendidikan Kimia dan Ilmu Kimia Jurnal Pengabdian Pada Masyarakat IPTEKS Medika: Jurnal Ilmiah Kesehatan
Ika Wahyuni
Universitas Nahdlatul Ulama Nusa Tenggara Barat, Mataram, Indonesia
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Other

Published : 5 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 5 Documents
Search

 1 
The Effect of Ashitaba (Angelica keiskei (Miq.) Koidz.)) Sap on the Total Cholesterol Levels of Cisplatin-Induced Wistar Rats Wahyuni, Ika; Aulifa, Diah L.; Rosdianto, Aziiz M.; Levita, Jutti
Pharmacology and Clinical Pharmacy Research Vol 8, No 3 (2023)
Publisher : Universitas Padjadjaran, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15416/pcpr.v8i3.51827

Abstract

Cisplatin is a platinum-based anticancer drug that, in long-term use, causes nephrotoxicity due to oxidative stress and increases total cholesterol and triglycerides in animal models. Angelica keiskei (Miq.) Koidz., (A. keiskei) or Japanese celery ashitaba, has been reported for its antioxidant and nephroprotective activity. This study aims to determine the activity of A. keiskei sap on total cholesterol levels of cisplatin-induced Wistar rats. The sap of A. keiskeiwas freeze-dried until a yield of 3.62% w/v was obtained. The fat content in A. keiskei sap powder was obtained at 7.36%. A total of 60 g of A. keiskei sap powder was macerated with 96% ethanol solvent (1:10) for 5 x 24 h until the ethanol extract of A. keiskei sap (ASEE) of 82.08% w/w was obtained. The pharmacology activity was conducted on male Wistar rats, which were divided into 5 groups, namely normal (treated with CMC Na 0.3%), negative (nephrotoxicity induced with cisplatin 5 mg/kg BW), positive (nephrotoxicity induced with cisplatin 5 mg/kg BW and treated with quercetin 20 mg/kg BW), and two test groups which were nephrotoxicity induced with cisplatin 5 mg/kg body weight and treated with ASEE 1000 mg/kg BW, and ASEE 1500 mg/ kg BW. It was found that neither dose of ASEE altered the total cholesterol levels in cisplatin-induced male Wistar rats and could maintain the cholesterol levels in the normal range.
Formulasi dan Evaluasi Sediaan Gel Hand Sanitizer Ekstrak Tangkai Sirih Merah (Piper crocatum) Gilang Pratama Putra; Lalu Sanik Wahyu Fadil Amrulloh; Ika Wahyuni; M. Ari Wisnu
Medika: Jurnal Ilmiah Kesehatan Vol. 4 No. 2 (2024): Medika: Jurnal Ilmiah Kesehatan
Publisher : Universitas Nahdlatul Ulama Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69503/medika.v4i2.979

Abstract

Tangkai sirih merah (Piper crocatum) mengandung beberapa senyawa seperti flavonoid, alkaloid, dan tanin yang berpotensi sebagai antimikroba. Ekstrak tangkai sirih merah (Piper crocatum) dibuat dengan metode maserasi menggunakan pelarut etanol 70%. Sediaan gel diformulasikan menggunakan kombinasi bahan seperti carbopol 940, gliserin, metil paraben, dan trietanolamin. Setelah dilakukan pembuatan formulasi gel, dilanjutkan evaluasi sediaan diantaranya uji organoleptik, homogenitas, pH (keasaman), daya sebar, viskositas (kekentalan), dan daya lekat. Berdasarkan hasil penelitian diperoleh sediaan gel hand sanitizer yang stabil secara fisik. Formulasi gel yang dihasilkan memiliki viskositas yang sesuai sehingga mudah diaplikasikan, dan memberikan sensasi lembut pada kulit.
TINJAUAN KIMIA FARMASI TERHADAP KARAKTERISTIK FARMASETIKA DAN EVALUASI DISOLUSI TABLET KOMBINASI AMLODIPIN BESILAT – LOSARTAN KALIUM Gilang Pratama Putra; Ika Wahyuni
JURNAL REDOKS : JURNAL PENDIDIKAN KIMIA DAN ILMU KIMIA Vol 9 No 1 (2026): Jurnal Redoks : Jurnal Pendidikan Kimia dan Ilmu Kimia
Publisher : Program Studi Pendidikan Kimia STKIP Bima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33627/re.v9i1.4259

Abstract

Penggunaan kombinasi obat amlodipin besilat dan losartan kalium pasien hipertensi bertujuan untuk menggantikan terapi tunggal yang kurang efektif. Sediaan kombinasi amlodipin besilat dan losartan kalium dikembangkan untuk memberikan efek sinergis dan meningkatkan kepatuhan pengobatan pasien hipertensi. Tujuan kajian artikel ini yaitu untuk mengetahui kombinasi tablet amlodipin besilat dan losartan kalium pada pasien hipertensi dari sisi farmakologi dan farmasetika. Metode yang digunakan dalam penelitian ini adalah pencarian artikel melalui database tunggal, yaitu Google Scholar. Kombinasi amlodipin besilat dan losartan kalium banyak digunakan pada pasien hipertensi stage II. Penggunaan amlodipin besilat dikombinasi dengan losartan dapat menurunkan tekanan darah secara signifikan dibandingkan penggunaan amlodipin secara monoterapi. Tablet lepas segera lapis ganda dipilih pada kombinasi kedua obat ini karena amlodipin besilat dan losartan kalium memiliki karakteristik yang berbeda, dimana formulasi amlodipin besilat tablet menggunakan kempa langsung dan losartan kalium menggunakan metode granulasi basah. Setelah pembuatan formulasi tablet kombinasi maka dilakukan evaluasi salah satunya uji disolusi. Uji disolusi dilakukan menggunakan alat disolusi USP Tipe II (tipe Paddle).
Edukasi Literasi Obat Berbasis Interaktif untuk Meningkatkan Pengetahuan Masyarakat di Pulau Sumbawa Ika Wahyuni; Gilang Pratama Putra; Lalu Sanik Wahyu Fadil Amrulloh; M Ari Wisnu; Jamiluddin Jamiluddin
Prima Abdika: Jurnal Pengabdian Masyarakat Vol. 6 No. 2 (2026): Volume 6 Nomor 2 Tahun 2026 (Juni 2026)
Publisher : Program Studi Pendidikan Guru Sekolah Dasar Universitas Flores Ende

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37478/abdika.v6i2.7689

Abstract

Low levels of medication literacy among communities and adolescents may lead to medication misuse, irrational self-medication, increased risk of adverse effects, and antibiotic resistance. Medication literacy encompasses the ability to access, understand, evaluate, and appropriately use medication-related information. This community service program aimed to improve medication literacy through interactive educational interventions in Sumbawa Island. The program employed interactive lectures, group discussions, medication-use simulations, and the distribution of educational materials. Activities were conducted in public areas and involved 50 respondents, consisting of adolescents and members of the general public. A pre-test and post-test design was used to evaluate improvements in participants’ ability to access, understand, evaluate, and use medication information. The results demonstrated significant improvements across all measured variables. Correct knowledge regarding appropriate sources of side-effect information (health professionals) increased from 30% to 100%. The ability to read and interpret medication dosage labels improved from 46% to 84%. Awareness of the need to complete prescribed antibiotics rose from 6% to 96%. Critical attitudes toward medication advertisements on social media also improved, with 82% of respondents indicating the need to verify information sources after the intervention. Practical skills in medication use increased substantially, including correct understanding of dosing intervals (from 2% to 78%) and appropriate emergency action by taking poisoning victims to healthcare facilities (from 40% to 100%). In conclusion, interactive medication literacy education effectively enhances knowledge, attitudes, and skills related to safe and rational medication use among communities and adolescents. This program is feasible for replication as part of broader public health strategies to strengthen health literacy.
Bakti Sosial Pemeriksaan Gratis Relawan Medis Beriuk Bareng Peduli di Desa Poton Bako Kecamatan Jerowaru, Kabupaten Lombok Timur M Ari Wisnu; Lalu Sanik Wahyu Fadil Amrulloh; Siti Amalia Wahyu Pratiwi; Widayanti Supraba; Gilang Pratama Putra; Ika Wahyuni; Zurhainun Mutmainnah; Hendriawan Hendriawan
Jurnal Pengabdian Pada Masyarakat IPTEKS Vol. 3 No. 2 (2026): Jurnal Pengabdian Pada Masyarakat IPTEKS, Maret 2026
Publisher : CV. Global Cendekia Inti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71094/jppmi.v3i2.200

Abstract

This community service activity was conducted in Poton Bako Village, Jerowaru District, where limited access to health services and low public awareness of routine health check-ups were identified. The activity aimed to improve access to healthcare services and promote early disease detection. A descriptive observational approach was used through a free health screening program involving 50 participants aged 3 to 45 years. The implementation included registration, vital signs examination, basic laboratory tests, medical examination by a general practitioner, as well as medication dispensing and education on proper drug use. The results showed that participants obtained initial information about their health conditions and demonstrated increased awareness of the importance of regular health check-ups. The activity also supported preventive efforts through health education and appropriate medication use. It was concluded that free health screening was effective in improving access to healthcare services and increasing community awareness of early disease detection.
Co-Authors Aulifa, Diah L. Gilang Pratama Putra Hendriawan Hendriawan Jamiluddin Jamiluddin Jutti Levita Lalu Sanik Wahyu Fadil Amrulloh Lalu Sanik Wahyu Fadil Amrulloh Lalu Sanik Wahyu Fadil Amrulloh M Ari Wisnu M Ari Wisnu M. Ari Wisnu Rosdianto, Aziiz M. Siti Amalia Wahyu Pratiwi Widayanti Supraba Zurhainun Mutmainnah