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All Journal Kwaghe International Journal of Sciences and Technology
Kabir Mustapha Umar
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Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Environmental Science Law, Crime, Criminology & Criminal Justice Social Sciences

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A Review on Antiplasmodial Activities of Hyptis suaveolens Plant Dauda Danlami; Ruqayyah Hamidu Muhammad; Kabir Mustapha Umar
Kwaghe International Journal of Sciences and Technology Vol 3 No 1 (2026): Kwaghe International Journal of Sciences and Technology
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/kijst.v3i1.9359

Abstract

Hyptis suaveolens (L.), a member of the Lamiaceae family, has long been used in traditional medicine and has recently attracted increasing attention for its antimalarial potential. This review synthesizes existing evidence on the antimalarial properties of H. suaveolens, with particular emphasis on its bioactive constituents, including flavonoids, terpenoids, and essential oils, which have demonstrated notable activity against malaria parasites. Evidence from both in vitro and in vivo studies indicates that extracts of H. suaveolens can inhibit Plasmodium species, particularly Plasmodium falciparum, the major causative agent of human malaria. The review further examines the proposed mechanisms underlying these effects, including inhibition of parasite growth, cytotoxic activity, and immunomodulatory responses. In addition, it highlights key challenges that must be addressed for therapeutic development, notably the standardization of plant extracts, clarification of toxicity profiles, and the need for rigorous clinical trials. Overall, the review underscores the promise of H. suaveolens as a potential source of novel antimalarial agents and contributes to ongoing efforts to identify plant-based alternatives for malaria treatment.
Co-Authors Dauda Danlami Ruqayyah Hamidu Muhammad