Restu Harisma Damayanti
Polytechnic Baubau. Jl. Lakarambau, Lipu, Kec. Betoambari, Kota Bau-Bau, Sulawesi Tenggara 93724, Indonesia

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Preparation Formulationlip Creamhenry Leaf Extract (Lawsonia Inermisl) As A Natural Dye Febi Arsita Safitri; Evi Mustiqawati; Restu Harisma Damayanti
Journal of Health Science and Pharmacy Vol. 3 No. 1 (2026): January - April
Publisher : Yayasan Cipta Anak Bangsa (YCAB) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/jhsp.v3i1.1559

Abstract

Background: Indonesia possesses abundant plant resources with significant potential for use as natural ingredients in cosmetic products, one of which is henna leaves (Lawsonia inermis L.). Henna leaves contain natural orange pigments that can be utilized as colorants. The distinctive orange hue of henna makes it a promising natural dye for decorative cosmetic products, particularly lip cream formulations, as an alternative to synthetic dyes. Objectives: This study aimed to formulate a lip cream preparation using henna leaf extract as a natural colorant and to evaluate the physical properties of the resulting formulations. Methods: Henna leaf extract was obtained through the maceration method using 70% ethanol as the solvent. The extract was then formulated into lip cream preparations with three different concentrations: F1 (2%), F2 (4%), and F3 (6%). Physical evaluation of the lip cream included organoleptic assessment, homogeneity test, spreadability test, and pH measurement. Results: The organoleptic evaluation showed that all formulations produced a brown-colored lip cream with a semi-solid consistency. Homogeneity testing indicated that all formulations were homogeneous. The pH values of F1, F2, and F3 were within the acceptable range for lip cream preparations. However, the spreadability test results revealed that none of the formulations met the specified requirements. Conclusion: Henna leaf extract demonstrates potential as a natural colorant in lip cream formulations. Nevertheless, further formulation development is required to improve the spreadability characteristics to achieve optimal physical quality of the product. Keywords: Henna Leaves, Formulation, Lip Cream, Natural Colorant
Knowledge, Attitudes, and Determinants of Beyond-Use Date (BUD) Drug Management in the Community Aprilia Syafaria; Evi Mustiqawati; Restu Harisma Damayanti
Journal of Health Science and Pharmacy Vol. 3 No. 1 (2026): January - April
Publisher : Yayasan Cipta Anak Bangsa (YCAB) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/jhsp.v3i1.1570

Abstract

Background: The obligation to include the Beyond Use Date (BUD) on medication containers constitutes an essential component of pharmaceutical management aimed at ensuring the safe, rational, and effective use of medicines. BUD refers to the time limit for the use of a drug product after compounding, preparation, or after the primary packaging has been opened or compromised. The absence of proper BUD labeling may increase the risk of medication misuse, as drugs used beyond their BUD may experience reduced stability, degradation of active substances, and potential negative health effects. Despite its importance, the implementation of BUD labeling on medication packaging in Indonesia remains limited. Objectives: This study aimed to determine the level of knowledge, attitudes, and associated factors related to Beyond Use Date (BUD) management of medicines among the community at Waborobo Public Health Center, Betoambari Subdistrict, Baubau City. Methods: This study employed a descriptive non-experimental design. The sampling technique used was purposive sampling, involving 88 respondents who sought outpatient treatment at Waborobo Public Health Center between May and June 2024. Primary data were collected using a structured questionnaire. Data were analyzed using descriptive statistical methods and the Chi-square test to examine associations between variables. Results: The results showed that, among 88 respondents, the majority demonstrated a fairly good level of knowledge regarding drug BUD management (74.14%). Additionally, 74.37% of respondents exhibited positive attitudes toward BUD management. Chi-square analysis revealed a significant association between knowledge of BUD management and educational background (p = 0.000; C = 0.527), as well as between knowledge and attitude (p = 0.000; C = 0.501). A significant relationship was also identified between educational background and attitudes toward BUD management (p = 0.025; C = 0.408). Conclusion: The community at Waborobo Public Health Center generally demonstrated fairly good knowledge and positive attitudes regarding Beyond Use Date (BUD) management of medicines. Educational background was significantly associated with knowledge and attitudes, indicating that education plays an important role in improving public awareness and appropriate medication management practices. Strengthening educational interventions may enhance proper BUD implementation in the community. Keywords: Beyond Use Date; medication management; community knowledge; attitudes; public health